Neuropsychopharmacology Reviews: The Next Generation of Progress
A series editorial by Salvatore J. Enna, Ph.D.
This volume represents the inaugural issue of Neuropsychopharmacology Reviews. As an annual publication, the offering is designed to provide authoritative and timely coverage of contemporary topics in the field. As subscribers to Neuropsychopharmacology, members of the College have early access to these reports both on line and in print.
Neuropsychopharmacology Reviews replaces the Generation of Progress, which consisted of five volumes published intermittently between 1968 and 2002. While the Generation of Progress served for decades as a major reference work, a single large volume is an increasingly difficult mechanism for promulgating new data given the pace of research, developments in information technology, and the time needed for authoring, editing, printing, and distributing such a massive work. After considering several alternatives, it was decided that a yearly publication of review articles is more easily managed, and makes possible more timely coverage of critical topics than is possible with a major reference work. Timely because the reviews are written shortly before the publication, and topical in that it will be possible to publish updates and perspectives on the same subject as often as warranted. To help ensure timeliness, the work includes a Hot Topics chapter that is prepared just prior to the production deadline. This section contains summaries of some of the most recent developments in the field. The volume also features downloadable graphics that can be used as a teaching resource. It is anticipated that the regular publication of this high-quality review journal will build a recognizable franchise, further establishing the College as the most authoritative source for information in the discipline.
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Volume One - Neuroplasticity
Editorials
Neuropsychopharmacology Reviews: The Next Generation of Progress
External Link Download PDFNeuroplasticity: A New Window on Therapeutics in Neuropsychiatric Disease
External Link Download PDFReviews
Neuroplasticity Mediated by Altered Gene Expression
External Link Download PDFSynaptic Plasticity: Multiple Forms, Functions, and Mechanisms
External Link Download PDFDivergent Plasticity of Prefrontal Cortex Networks
External Link Download PDFHot Topics
Hot Topics
External Link Download PDF
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Volume Two - CNS Drug Discovery & Development
Editorials
CNS Drug Discovery and Development: When Will We Rescue Tantalus?' Neuropsychopharmacology Reviews Volume 2 on CNS Drug Discovery and Development: Challenges and Opportunities
Download PDFPhysician-Scientist's Frustrations Fester
External Link Download PDFReviews
The Medical and Economic Roles of Pipeline Pharmacogenetics: Alzheimer's Disease as a Model of Efficacy and HLA-B*5701 as a Model of Safety
External Link Download PDFTarget Identification for CNS Diseases by Transcriptional Profiling
External Link Download PDFIn Vitro and In Vivo Pharmacological Models to Assess Demyelination and Remyelination
External Link Download PDFRemoving Obstacles in Neuroscience Drug Discovery: The Future Path for Animal Models
External Link Download PDFDrugability of Extracellular Targets: Discovery of Small Molecule Drugs Targeting Allosteric, Functional, and Subunit-Selective Sites on GPCRs and Ion Channels
External Link Download PDFSmall Molecule Protein-Protein Interaction Inhibitors as CNS Therapeutic Agents: Current Progress and Future Hurdles
External Link Download PDFNovel Therapeutic Modalities to Address Nondrugable Protein Interaction Targets
External Link Download PDFPharmacogenomics
External Link Download PDFMetabolomics: A Global Biochemical Approach to the Study of Central Nervous System Diseases
External Link Download PDFThe Role of Imaging in Proof of Concept for CNS Drug Discovery and Development
External Link Download PDFBridging Bench and Practice: Translational Research for Schizophrenia and Other Psychotic Disorders
External Link Download PDFChallenges in Developing Novel Treatments for Childhood Disorders: Lessons from Research on Anxiety
External Link Download PDFNIMH Initiatives to Facilitate Collaborations Among Industry, Academia, and Government for the Discovery and Clinical Testing of Novel Models and Drugs for Psychiatric Disorders
External Link Download PDFHot Topics
Adult neurogenesis, cell cycle and drug discovery in psychiatry
External Link Download PDFTargeting nicotinic receptor antagonists as novel pharmacotherapies for tobacco dependence and relapse
External Link Download PDFRNA editing as a therapeutic target for CNS disorders
External Link Download PDFThe dynorphin / kappa opioid receptor system: a new target for the treatment of addiction and affective disorders?
External Link Download PDFProtein-protein interactions as therapeutic targets in neuropsychopharmacology
External Link Download PDFPromise of mGluR2/3 activators in psychiatry
External Link Download PDFTargeting AMPA and kainate receptors in neurological disease: therapies on the horizon?
External Link Download PDFGene expression profiling in blood: new diagnostics in alcoholism and addiction?
External Link Download PDFFrom rapid In Vitro screening to rapid In Vivo screening in the drug discovery process
External Link Download PDFTargeting the serotonin 2c receptor for the treatment of obesity and type 2 diabetes
External Link Download PDFTurning up the pace of ion channel screening in drug discovery
External Link Download PDFLewy body pathology in long-term fetal nigral transplants: is parkinson's disease transmitted from one neural system to another?
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Volume Three - Neurocircuitry: A Window into the Network Underlying Neuropsychiatric Disease
Editorials
Neurocircuitry: A Window into the Networks Underlying Neuropsychiatric Disease
External Link Download PDFReviews
The Reward Circuit: Linking Primate Anatomy and Human Imaging
External Link Download PDFCortico-Basal Ganglia Reward Network: Microcircuitry
External Link Download PDFHuman and Rodent Homologies in Action Control: Corticostriatal Determinants of Goal-Directed and Habitual Action
External Link Download PDFThe Neural Circuitry of Executive Functions in Healthy Subjects and Parkinson's Disease
External Link Download PDFThe Episodic Memory System: Neurocircuitry and Disorders
External Link Download PDFPhasic vs Sustained Fear in Rats and Humans: Role of the Extended Amygdala in Fear vs Anxiety
External Link Download PDFChanging Fear: The Neurocircuitry of Emotion Regulation
External Link Download PDFNormal Development of Brain Circuits
External Link Download PDFThe Neurocircuitry of Fear, Stress, and Anxiety Disorders
External Link Download PDFNeurocircuitry of Mood Disorders
External Link Download PDFNeurocircuitry of Addiction
External Link Download PDFAmygdalocortical Circuitry in Schizophrenia: From Circuits to Molecules
External Link Download PDFExecutive Function, Neural Circuitry, and Genetic Mechanisms in Schizophrenia
External Link Download PDFAttention-Deficit / Hyperactivity Disorder and Attention Networks
External Link Download PDFNoninvasive techniques for probing neurocircuitry and treating illness: vagus nerve stimulation (VNS), transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS)
External Link Download PDFInvasive Circuitry-Based Neurotherapeutics: Stereotactic Ablation and Deep Brain Stimulation for OCD
External Link Download PDFHot Topics
The Role of the ventral pallidum in psychiatric disorders
External Link Download PDFExploring the molecular basis of addiction: drug-induced neuroadaptations
External Link Download PDFThe emerging role of integrins in neuropsychiatric disorders
External Link Download PDFImaging advances in developing new medications for addiction
External Link Download PDFSex-related functional asymmetry in the limbic brain
External Link Download PDFDissecting the neural circuitry of addiction and psychiatric disease with optogenetics
External Link Download PDFNeurocartography
External Link Download PDFModafinil: an anti-relapse medication
External Link Download PDFTrick or treat? neurodevelopmental consequences of pharmacotherapy for affective disorders
External Link Download PDFLigand functional selectivity advances our understanding of drug mechanisms and drug discovery
External Link Download PDFInduced pluripotent stem (iPS) cells and their future in psychiatry
External Link Download PDFAdvances in PET analyses of stress and dopamine
External Link Download PDFImaging and genetics advances in understanding geriatric depression
External Link Download PDFNeuronal signaling pathways: genetic insights into the pathophysiology of major mental illness
External Link Download PDFAntidepressants, age, and neuroprogenitors
External Link Download PDFNormalizing drug-induced neuronal plasticity in nucleus accumbens weakens enduring drug-seeking behavior
External Link Download PDFOrexin/hypocretin in psychiatric disorders: present state of knowledge and future potential
External Link Download PDFNew vaccine development for chronic brain disease
External Link Download PDFConvergent Functional Genomics: what we have learned and can learn about genes, pathways, and mechanisms
External Link Download PDF
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Volume Four - Cognition
Editorials
Cognition: The Ultimate Brain Function
External LinkReviews
Neuroanatomical and Neurochemical Substrates of Timing
External LinkHow Human Electrophysiology Informs Psychopharmacology: from Bottom-up Driven Processing to Top-Down Control
External LinkModes and Models of Forebrain Cholinergic Neuromodulation of Cognition
External LinkOpponency Revisited: Competition and Cooperation Between Dopamine and Serotonin
External LinkSerotonin and Dopamine: Unifying Affective, Activational, and Decision Functions
External LinkThe Roles of Dopamine and Serotonin in Decision Making: Evidence from Pharmacological Experiments in Humans
External LinkNeurogenetics and Pharmacology of Learning, Motivation, and Cognition
External LinkAffective Cognition and its Disruption in Mood Disorders
External LinkFrontocingulate Dysfunction in Depression: Toward Biomarkers of Treatment Response
External LinkUnderstanding the Effects of Stimulant Medications on Cognition in Individuals with Attention-Deficit Hyperactivity Disorder: A Decade of Progress
External LinkPharmacological Enhancement of Memory and Executive Functioning in Laboratory Animals
External LinkUpdate on Memory Systems and Processes
External LinkGlutamate Receptors in Extinction and Extinction-Based Therapies for Psychiatric Illness
External LinkGlutamatergic Model Psychoses: Prediction Error, Learning, and Inference
External LinkGlutamatergic Model Psychoses: Prediction Error, Learning, and Inference
External LinkCognitive Control Deficits in Schizophrenia: Mechanisms and Meaning
External LinkHow Placebos Change the Patient's Brain
External LinkHot Topics
Neurocognitive Dimensions of Breast Cancer and Its Treatment
External LinkNICO-TEEN: Neural Substrates that Mediate Adolescent Tobacco Abuse
External LinkEpigenetic Modifications in Neurons are Essential for Formation and Storage of Behavioral Memory
External LinkEmerging Roles for Ectonucleotidases in Pain-Sensing Neurons
External LinkGambling Rats: Insight into Impulsive and Addictive Behavior
External LinkInsulin Regulation of Monoamine Signaling: Pathway to Obesity
External LinkExtinction Learning and Adult Neurogenesis
External LinkTranscriptional Control of Serotonin-Modulated Behavior and Physiology
External LinkAn Emerging Role for TARPs in Neuropsychiatric Disorders
External LinkNew Horizons for Selective 5-HT2C Receptor Ligands in Psychiatric/Neurological Disorders
External LinkModeling Neuropsychiatric Disease-Relevant Human SNPs in Mice
External LinkCortical Circuits for Motor Control
External LinkOral Methylphenidate Normalizes Cingulate Activity and Decreases Impulsivity in Cocaine Addiction During an Emotionally Salient Cognitive Task
External LinkFailures in Learning-Dependent Predictive Perception as the Key Cognitive Vulnerability to Psychosis in Schizophrenia
External LinkNew Insights into the Mechanisms Underlying the Effects of BDNF on Eating Behavior
External LinkThe Therapeutic Potential of κ-Opioids for Treatment of Pain and Addiction
External LinkNew Treatments in Amyotrophic Lateral Sclerosis
External LinkfMRI Studies of Reward Processing in Adolescent Depression
External LinkDorsal vs Ventral Hippocampal Neurogenesis: Implications for Cognition and Mood
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Volume Five - Neurotherapeutics
Editorials
Neurotherapeutics
External LinkReviews
From Revolution to Evolution: The Glutamate Hypothesis of Schizophrenia and its Implication for Treatment
External LinkMuscarinic and Nicotinic Acetylcholine Receptor Agonists and Allosteric Modulators for the Treatment of Schizophrenia
External LinkCognitive Training for Impaired Neural Systems in Neuropsychiatric Illness
External LinkReview of Pharmacological Treatment in Mood Disorders and Future Directions for Drug Development
External LinkSomatic Treatments for Mood Disorders
External LinkCognitive Mechanisms of Treatment in Depression
External LinkPsychoneuroimmunology Meets Neuropsychopharmacology: Translational Implications of the Impact of Inflammation on Behavior
External LinkNovel Therapeutic Strategies for Alcohol and Drug Addiction: Focus on GABA, Ion Channels and Transcranial Magnetic Stimulation
External LinkTherapeutic Strategies in Fragile X Syndrome: Dysregulated mGluR Signaling and Beyond
External LinkNetworking in Autism: Leveraging Genetic, Biomarker and Model System Findings in the Search for New Treatments
External LinkParkinson's Disease Therapeutics: New Developments and Challenges Since the Introduction of Levodopa
External LinkEpigenetic Treatments for Cognitive Impairments
External LinkAlzheimer's Therapeutics: Translation of Preclinical Science to Clinical Drug Development
External LinkCommentary
New Era for Novel CNS Drug Development
External LinkTranslating Discoveries into Medicine: Psychiatric Drug Development in 2011
External LinkNIA Commentary: Translational Issues in Alzheimer's Disease Drug Development
External LinkNeuroscience Networking: Linking Discovery to Drugs
External LinkNew Medications for Substance Use Disorders: Challenges and Opportunities
External LinkThe Role of Complementary, Alternative, and Integrative Medicine in Personalized Health Care
External LinkHot Topics
Grateful DREADDs: Engineered Receptors Reveal How Neural Circuits Regulate Behavior
External LinkDopamine D3 Receptor Function and Cocaine Exposure
External LinkChronic N-acetylcysteine after cocaine self-administration produces enduring reductions in drug-seeking
External LinkMethamphetamine-Induced Oxidation of Proteins and Alterations in Protein Processing
External LinkPlacental Source for 5-HT that Tunes Fetal Brain Development
External LinkMainstreaming Mice
External LinkPhospholipase D as a Therapeutic Target in Brain Disorders
External LinkTransferrin Antibodies Into the Brain
External LinkEndogenous Opioids as Physiological Antidepressants: Complementary Role of Delta Receptors and Dopamine
External LinkOxytocin as a Potential Therapeutic Target for Schizophrenia and Other Neuropsychiatric Conditions
External LinkDysregulation of mTOR Signaling in Neuropsychiatric Disorders: Therapeutic Implications
External LinkHabenular Signaling in Nicotine Reinforcement
External LinkCircuits, Cells, and Synapses: Toward a New Target for Deep Brain Stimulation in Depression
External LinkUpdate on Corticotropin-Releasing Factor Pharmacotherapy for Psychiatric Disorders: A Revisionist View
External LinkUpdate on Omega-3 Polyunsaturated Fatty Acids in Early-Stage Psychotic Disorders
External LinkBeyond Antipsychotics: Pharmacologically-Augmented Cognitive Therapies (PACTs) for Schizophrenia
External LinkFrom Father to Offspring: Paternal Transmission of Depressive-Like Behaviors
External LinkView the NPPR Nature website
External Link
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Volume Six - Epigenetics
Editorials
Epigenetic Mechanisms in Psychiatry
External LinkReviews
Histone Regulation in the CNS: Basic Principles of Epigenetic Plasticity
External LinkDNA Methylation and Its Basic Function
External LinkGeneral Principals of miRNA Biogenesis and Regulation in the Brain
External LinkRandom and Non-Random Monoallelic Expression
External LinkThe Role of Histone Acetylation in Memory Formation and Cognitive Impairments
External LinkEpigenetic Mechanisms in Learned Fear: Implications for PTSD
External LinkHot Topics
Estrogen and Leptin Regulation of Endocrinological Features of Anorexia Nervosa
External LinkTranscriptional Plasticity in the Brain following Metabolic Challenge
External LinkNeurobiological Correlates of the Familial Risk for Stimulant Drug Dependence
External LinkEpigenetic Regulation of Synapsin Genes in Mood Disorders
External LinkNeuroinflammation and Autism: Toward Mechanisms and Treatments
External LinkCognitive Training for Psychiatric Disorders
External Link
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Volume Seven - Biomolecular Discovery
Editorials
Frontiers of Biomolecular Exploration in Brain Disorders
External LinkReviews
Integrative Biological Analysis For Neuropsychopharmacology
External LinkMass Spectrometry Strategies for Clinical Metabolomics and Lipidomics in Psychiatry, Neurology, and Neuro-Oncology
External LinkMass Spectrometry Imaging, an Emerging Technology in Neuropsychopharmacology
External LinkSmall-Volume Analysis of Cell–Cell Signaling Molecules in the Brain
External LinkPostmortem Brain: An Underutilized Substrate for Studying Severe Mental Illness
External LinkHot Topics
Neurobiology of Rapid Acting Antidepressants: Role of BDNF and GSK-3β
External LinkSeeing the Future: Epigenetic Biomarkers of Postpartum Depression
External LinkCell Adhesion Molecules: Druggable Targets for Modulating the Connectome and Brain Disorders?
External LinkCircuits in Sync: Decoding Theta Communication in Fear and Safety
External Link
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Volume Eight - Neurodevelopment and the Origins of Brain Disorders
Editorials
Neurodevelopment and the Origins of Brain Disorders
External LinkReviews
Synapse Assembly and Neurodevelopmental Disorders
External LinkDevelopment of Cortical Interneurons
External LinkDevelopmental Perspectives on Oxytocin and Vasopressin
External LinkChild Psychiatry Branch of the National Institute of Mental Health Longitudinal Structural Magnetic Resonance Imaging Study of Human Brain Development
External LinkSensitive Periods in Affective Development: Nonlinear Maturation of Fear Learning
External LinkDevelopmental Consequences of Fetal Exposure to Drugs: What We Know and What We Still Must Learn
External LinkHot Topics
In vivo Calcium Imaging to Illuminate Neurocircuit Activity Dynamics Underlying Naturalistic Behavior
External LinkDREAMM: A Biobehavioral Imaging Methodology for Dynamic In Vivo Whole-Brain Mapping of Cell Type-Specific Functional Networks
External LinkMore than a Gut Feeling: the Microbiota Regulates Neurodevelopment and Behavior
External LinkMemory Allocation
External LinkOxytocin, Social Cognition and Psychiatry
External LinkFKBP5 Allele-Specific Epigenetic Modification in Gene by Environment Interaction
External Link
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Volume Nine - Impact of Stress on the Brain: Pathology, Treatment and Prevention
Editorials
Impact of Stress on the Brain: Pathology, Treatment and Prevention
External LinkReviews
Stress Effects on Neuronal Structure: Hippocampus, Amygdala, and Prefrontal Cortex
External LinkAdult Hippocampal Neurogenesis, Fear Generalization, and Stress
External LinkInduction and Expression of Fear Sensitization Caused by Acute Traumatic Stress
External LinkStress and Fear Extinction
External LinkNeurobiological Interactions Between Stress and the Endocannabinoid System
External LinkStress Modulation of Opposing Circuits in the Bed Nucleus of the Stria Terminalis
External LinkThe Human BNST: Functional Role in Anxiety and Addiction
External LinkDifferential Susceptibility of the Developing Brain to Contextual Adversity and Stress
External LinkThe Neuro-Environmental Loop of Plasticity: A Cross-Species Analysis of Parental Effects on Emotion Circuitry Development Following Typical and Adverse Caregiving
External LinkEarly Adverse Experiences and the Developing Brain
External LinkToward Understanding How Early-Life Stress Reprograms Cognitive and Emotional Brain Networks
External LinkThe Placenta as a Mediator of Stress Effects on Neurodevelopmental Reprogramming
External LinkModels of Intergenerational and Transgenerational Transmission of Risk for Psychopathology in Mice
External LinkIntergenerational Transmission of Stress in Humans
External LinkGenetic Approaches to Hypothalamic-Pituitary-Adrenal Axis Regulation
External LinkGene–Stress–Epigenetic Regulation of FKBP5: Clinical and Translational Implications
External LinkGenetic Moderation of Stress Effects on Corticolimbic Circuitry
External LinkThe Genetics of Stress-Related Disorders: PTSD, Depression, and Anxiety Disorders
External LinkNeuroimaging of Fear-Associated Learning
External LinkStress-Induced Reinstatement of Drug Seeking: 20 Years of Progress
External LinkPrevention of Trauma and Stressor-Related Disorders: A Review
External LinkHot Topics
Rehebbilitating Memory
External LinkExtracellular Vesicles: Goodies for the Brain?
External LinkNew Signaling Pathway for Gut–Brain Interactions
External LinkNeural Basis of Mindfulness Interventions that Moderate the Impact of Stress on the Brain
External LinkDynorphin, Dysphoria, and Dependence: the Stress of Addiction
External LinkRiboTag: Not Lost in Translation
External LinkPharmacological Treatments for Autism Spectrum Disorder: Will Emerging Approaches Yield New Treatments?
External LinkNicotine-Targeting Nano-Vaccines for Smoking Cessation
External LinkNeurochips Enable Nanoscale Devices for High-Resolution In Vivo Neurotransmitter Sensing
External LinkClosing the Loop in Deep Brain Stimulation for Psychiatric Disorders: Lessons from Motor Neural Prosthetics
External LinkHeteroreceptor Complexes and their Allosteric Receptor–Receptor Interactions as a Novel Biological Principle for Integration of Communication in the CNS: Targets for Drug Development
External LinkHippocampal Neurogenesis and Memory Clearance
External LinkTranslational Studies of Sex Differences in Sensitivity to Opioid Addiction
External LinkHormone modulation improves cognition in schizophrenia
External LinkNeurobiology of Compulsive Sexual Behavior: Emerging Science
External LinkSomatic DNA Variation in Brain as a Source of Risk for CNS Diseases
External LinkPsychiatric Illnesses as Oscillatory Connectomopathies
External LinkThe Cellular Sequelae of Early Stress: Focus on Aging and Mitochondria
External Link
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Volume Ten - The Immunology of Behavior—Exploring the Role of the Immune System in Brain Health and Illness
Editorials
The Immunology of Behavior—Exploring the Role of the Immune System in Brain Health and Illness
External LinkReviews
Pathogen–Host Defense in the Evolution of Depression: Insights into Epidemiology, Genetics, Bioregional Differences and Female Preponderance
External LinkCentral Nervous System: (Immunological) Ivory Tower or Not?
External LinkDanger Signals and Inflammasomes: Stress-Evoked Sterile Inflammation in Mood Disorders
External LinkRepeated Social Defeat, Neuroinflammation, and Behavior: Monocytes Carry the Signal
External LinkImmune and Neuroendocrine Mechanisms of Stress Vulnerability and Resilience
External LinkGenetic Contributions of Inflammation to Depression
External LinkPsychoneuroimmunology of Early-Life Stress: The Hidden Wounds of Childhood Trauma?
External LinkRole of Adiposity-Driven Inflammation in Depressive Morbidity
External LinkSleep Health: Reciprocal Regulation of Sleep and Innate Immunity
External LinkGlial and Neuroimmune Mechanisms as Critical Modulators of Drug Use and Abuse
External LinkMicrobes, Immunity, and Behavior: Psychoneuroimmunology Meets the Microbiome
External LinkInflammation, Glutamate, and Glia: A Trio of Trouble in Mood Disorders
External LinkInflammation Effects on Motivation and Motor Activity: Role of Dopamine
External LinkIn Sickness and in Health: The Co-Regulation of Inflammation and Social Behavior
External LinkInflammation in Fear- and Anxiety-Based Disorders: PTSD, GAD, and Beyond
External LinkRole of Inflammation in Suicide: From Mechanisms to Treatment
External LinkThe Role of the Immune System in Autism Spectrum Disorder
External LinkTowards an Immunophenotype of Schizophrenia: Progress, Potential Mechanisms, and Future Directions
External LinkMicroglia Priming with Aging and Stress
External LinkTherapeutic Implications of Brain–Immune Interactions: Treatment in Translation
External LinkHot Topics
Dissecting Suicidality Using a Combined Genomic and Clinical Approach
External LinkFood Addiction and Obesity
External LinkThe Emerging Role of Innate Immunity in Alzheimer’s Disease
External LinkPramipexole in Treatment Resistant-Depression, Possible Role of Inflammatory Cytokines
External LinkModeling the Impact of Social Contact on Substance Use
External LinkImpact on Cortical Function of Cocaine Abuse Co-Occurring with HIV
External LinkMirror Neurons in Psychiatric Disorders: from Neuroception to Bio-behavioral System Dysregulation
External LinkThe Cannabinoid Receptor 1 as a Key Mediator of Adolescent Behavior
External LinkProspects for Medications to Reverse Causative Epigenetic Processes in Neuropsychiatry Disorders
External LinkKetamine Mechanism of Action: Separating the Wheat from the Chaff
External LinkThe Direct and Indirect Pathways of the Nucleus Accumbens are not What You Think
External LinkTherapeutic Potential of Conjugated siRNAs for the Treatment of Major Depressive Disorder
External LinkError Processing in Depressive States: A Translational Opportunity?
External LinkImaging Adult Hippocampal Neurogenesis In Vivo
External LinkEmerging Epigenetic Therapies in Neuroscience: Focus on Bromodomain-Containing Drug Targets
External LinkREM Sleep on It!
External LinkThe Neuroimmune Basis of Excessive Alcohol Consumption
External LinkOxytocin-Augmented Psychotherapy: Beware of Context
External LinkA Self-Generated Environmental Factor as a Potential Contributor to Atypical Early Social Communication in Autism
External Link
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Volume Eleven - Cannabis and Cannabinoids: From Synapse to Society
Editorials
Cannabis and Cannabinoids: From Synapse to Society
External LinkReviews
CB1 Receptor Signaling in the Brain: Extracting Specificity from Ubiquity
External LinkThe Role of the Endocannabinoid System and Genetic Variation in Adolescent Brain Development
External LinkSex-Dependent Effects of Cannabis and Cannabinoids: A Translational Perspective
External LinkThe Endogenous Cannabinoid System: A Budding Source of Targets for Treating Inflammatory and Neuropathic Pain
External LinkIntegrating Endocannabinoid Signaling and Cannabinoids into the Biology and Treatment of Posttraumatic Stress Disorder
External LinkEndocannabinoid Regulation of Reward and Reinforcement through Interaction with Dopamine and Endogenous Opioid Signaling
External LinkPreclinical Studies of Cannabinoid Reward, Treatments for Cannabis Use Disorder, and Addiction-Related Effects of Cannabinoid Exposure
External LinkClinical and Preclinical Evidence for Functional Interactions of Cannabidiol and Δ9-Tetrahydrocannabinol
External LinkCirculating Endocannabinoids: From Whence Do They Come and Where are They Going?
External LinkThe Current State of Pharmacological Treatments for Cannabis Use Disorder and Withdrawal
External LinkUS Epidemiology of Cannabis Use and Associated Problems
External LinkHot Topics
Toward a Translationally Relevant Preclinical Model of Cannabis Use
External LinkSetting the Legal Age for Access to Cannabis in Canada: Bridging Neuroscience, Policy, and Prevention
External LinkMedical Cannabis Research: Issues and Priorities
External LinkSelective Adenylyl Cyclase Type 1 Inhibitors as Potential Opioid Alternatives For Chronic Pain
External LinkNovel Synthetic Opioids and Overdose Deaths: Tip of the Iceberg?
External LinkOpioidergic regulation of pain and pleasure in human social relationships
External LinkModulating Amygdala–Hippocampal Network Communication: A Potential Therapy for Neuropsychiatric Disorders
External LinkModeling Non-Syndromic Autism with Human-Induced Pluripotent Stem Cells
External LinkInnovative Therapeutic Intervention For Opioid Use Disorder
External LinkThe Ketamine Metabolite 2R,6R-Hydroxynorketamine Blocks NMDA Receptors and Impacts Downstream Signaling Linked to Antidepressant Effects
External LinkCognitive Signaling in Cerebellar Granule Cells
External LinkThe Promise of Genome Editing for Modeling Psychiatric Disorders
External LinkAggression Addiction and Relapse: A New Frontier in Psychiatry
External LinkComputational Approaches to Behavior Analysis in Psychiatry
External LinkCannabinoid Receptor 1 Positive Allosteric Modulators for Posttraumatic Stress Disorder
External LinkIntegrating ‘Omics’ Approaches to Prioritize New Pathogenetic Mechanisms for Mental Disorders
External LinkA Translational Model to Assess Sign-Tracking and Goal-Tracking Behavior in Children
External LinkThe Role of Mitochondrial Glutamate Metabolism in Cognitive Development and Disease
External LinkCross-Species Neurophysiological Biomarkers of Attentional Dysfunction in Schizophrenia: Bridging the Translational Gap
External Link
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Volume Twelve - Sex Matters
Editorials
Sex matters
External LinkNeuropsychopharmacology (NPP): gender balance in journal function
External LinkReviews
Sex differences in psychiatric disorders: what we can learn from sex chromosome aneuploidies
External LinkWhat has sex got to do with it? The role of hormones in the transgender brain
External LinkSex differences in neuroimmunity as an inherent risk factor
External LinkSex differences in the hypothalamic–pituitary–adrenal axis’ response to stress: an important role for gonadal hormones
External LinkSex differences in major depression and comorbidity of cardiometabolic disorders: impact of prenatal stress and immune exposures
External LinkSex differences in the developing brain: insights from multimodal neuroimaging
External LinkLet’s call the whole thing off: evaluating gender and sex differences in executive function
External LinkSex-dependent regulation of social reward by oxytocin: an inverted U hypothesis
External LinkSex differences and the neurobiology of affective disorders
External LinkSex differences in stress reactivity in arousal and attention systems
External LinkSex differences in antidepressant efficacy
External LinkNeuronal and glial factors contributing to sex differences in opioid modulation of pain
External LinkSex differences in neural mechanisms mediating reward and addiction
External LinkInflaming sex differences in mood disorders
External LinkSex differences in hippocampal cognition and neurogenesis
External LinkHot Topics
Antidepressant potential of metabotropic glutamate receptor mGlu2 and mGlu3 negative allosteric modulators
External LinkTinkering with THC-to-CBD ratios in Marijuana
External LinkSex differences in schizophrenia: estrogen and mitochondria
External LinkVaccines to treat opioid use disorders and to reduce opioid overdoses
External LinkRegulation of raphe serotonin neurons by serotonin 1A and 2B receptors
External LinkDynamic network targeting for closed-loop deep brain stimulation
External LinkNMDA-receptor independent actions of ketamine: a new chapter in a story that’s not so old
External LinkLipid signalling in the mesolimbic dopamine pathway
External LinkAmyloid oligomer interactions and polymorphisms: disease-relevant distinct assembly of α-synuclein and tau
External LinkOvarian hormones, genes, and the brain: the case of estradiol and the brain-derived neurotrophic factor (BDNF) gene
External LinkSex differences in the incidence of antidepressant-induced mania (AIM) in bipolar disorders
External LinkGuidance cues: linking drug use in adolescence with psychiatric disorders
External LinkThe ventromedial prefrontal cortex: a putative locus for trait inattention
External LinkAre lithium effects dependent on genetic/epigenetic architecture?
External LinkUnique treatment potential of cannabidiol for the prevention of relapse to drug use
External LinkPositive-allosteric modulation of the 5-HT2C receptor: implications for neuropsychopharmacology and neurotherapeutics
External LinkMotion mapping in humans as a biomarker for psychiatric disorders
External LinkTreating cue-reactivity with brain stimulation: a new (transdiagnostic) approach
External LinkDecoding the role of the microbiome on amygdala function and social behaviour
External LinkNovel models of drug relapse and craving after voluntary abstinence
External LinkAn emerging epigenetic framework of systemic and central mechanisms underlying stress-related disorders
External Link
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Volume Thirteen - Sleep and Neuropsychiatric Illness
Editorials
Sleep and neuropsychiatric illness
External LinkPerspective: Drugs, sleep, and the addicted brain
External LinkReviews
Arousal and sleep circuits
External LinkSleep deprivation, vigilant attention, and brain function: a review
External LinkNeurochemical mechanisms for memory processing during sleep: basic findings in humans and neuropsychiatric implications
External LinkGenetics of the human circadian clock and sleep homeostat
External LinkSleep disturbance in PTSD and other anxiety-related disorders: an updated review of clinical features, physiological characteristics, and psychological and neurobiological mechanisms
External LinkSleep, insomnia, and depression
External LinkSleep as a translationally-relevant endpoint in studies of autism spectrum disorder (ASD)
External LinkBidirectional relationship between sleep and Alzheimer’s disease: role of amyloid, tau, and other factors
External LinkSleep in Parkinson’s disease
External LinkSleep and neurological autoimmune diseases
External LinkAlcohol use disorder and sleep disturbances: a feed-forward allostatic framework
External LinkSleep therapeutics and neuropsychiatric illness
External LinkSleep in the United States Military
External LinkIntegrating sleep, neuroimaging, and computational approaches for precision psychiatry
External LinkSleep deficiency and chronic pain: potential underlying mechanisms and clinical implications
External LinkHot Topics
MDMA enhances pleasantness of affective touch
External LinkIntra-individual changes in methylome profiles: an epigenetic ‘scar’ of early-life adversity?
External LinkThe upside of stress: a mechanism for the positive motivational role of corticotropin releasing factor
External LinkDopamine release drives motivation, independently from dopamine cell firing
External LinkPhysiological roles for neuromodulation via Gi/o GPCRs working through Gβγ–SNARE interaction
External LinkThe striatum specifies the statistics of behavior
External LinkContributions of nonneuronal brain cells in substance use disorders
External LinkTRPV1 and MOR working in tandem: implications for pain and opioids use
External LinkTowards objective definition of psychopathology in post-traumatic stress disorder
External LinkLinking actions with their consequences within the ventrolateral orbital cortex
External LinkRegulation of fear extinction and relapse by hippocampal engrams
External LinkThe complexity of pharmacology of cannabidiol (CBD) and its implications in the treatment of brain disorders
External LinkIs depression a disorder of electrical brain networks?
External LinkMDMA-assisted psychotherapy for posttraumatic stress disorder: A promising novel approach to treatment
External LinkSpatial transcriptomics: putting genome-wide expression on the map
External LinkRole for kappa-opioid system in stress-induced cocaine use uncovered with PET
External LinkTargeting neuroinflammation with brain penetrant P2X7 antagonists as novel therapeutics for neuropsychiatric disorders
External LinkBiological fingerprints for psychosis
External LinkSelection criteria for neurophysiologic biomarkers to accelerate the pace of CNS therapeutic development
External LinkSleep and EEG biomarkers as avenues toward new treatment approaches in Angelman syndrome
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Volume Fourteen - Big data in Psychiatry: Multiomics, Neuroimaging, Computational Modeling, and Digital Phenotyping
Editorials
Big data in psychiatry: multiomics, neuroimaging, computational modeling, and digital phenotyping
External LinkReviews
Advances in the computational understanding of mental illness
External LinkModeling brain, symptom, and behavior in the winds of change
External LinkBig behavior: challenges and opportunities in a new era of deep behavior profiling
External LinkOpportunities and challenges in the collection and analysis of digital phenotyping data
External LinkLeveraging large genomic datasets to illuminate the pathobiology of autism spectrum disorders
External LinkPsychENCODE and beyond: transcriptomics and epigenomics of brain development and organoids
External LinkInterpretation of psychiatric genome-wide association studies with multispecies heterogeneous functional genomic data integration
External LinkSystems-based proteomics to resolve the biology of Alzheimer’s disease beyond amyloid and tau
External LinkSignature-based approaches for informed drug repurposing: targeting CNS disorders
External LinkThe ABCD study: understanding the development of risk for mental and physical health outcomes
External LinkBiotyping in psychosis: using multiple computational approaches with one data set
External LinkDissecting diagnostic heterogeneity in depression by integrating neuroimaging and genetics
External LinkDeep learning for small and big data in psychiatry
External LinkDigital health data-driven approaches to understand human behavior
External LinkReal-time mobile monitoring of bipolar disorder: a review of evidence and future directions
External LinkToward dynamic phenotypes and the scalable measurement of human behavior
External LinkHot Topics
Covid-19 and promising solutions to combat symptoms of stress, anxiety and depression
External LinkImaging suicidal thoughts and behavior: the promise of computational models
External LinkCritical roles for developmental hormones and genetic sex in stress-induced transcriptional changes associated with depression
External LinkEEG microstate sequences suggest abnormally chaotic brain dynamics in psychosis
External LinkDNA methylation clock associated with age-related illnesses is accelerated in PTSD
External LinkAstrocyte adenosine signaling and neural mechanisms of goal-directed and habitual reward-seeking behaviors
External LinkA prefrontal social circuit vulnerable to juvenile social isolation
External LinkBiologically plausible models of neural dynamics for rapid-acting antidepressant interventions
External LinkThe critical importance in identifying the biological mechanisms underlying the effects of racism on mental health
External LinkChromatin architecture provides a roadmap to improve our understanding of psychiatric disorders
External LinkTargeting persistent stress-enhanced memory through microRNAs
External LinkDimensional approaches to understanding threat conditioning and extinction in anxiety
External Link“Next up for psychiatry: rejection sensitivity and the social brain”
External LinkGenetic and epigenetic modulation of the oxytocin receptor and implications for autism
External LinkComputational phenotyping and longitudinal dynamics to inform clinical decision-making in psychiatry
External LinkReinforcing actions through the thalamostriatal circuit
External LinkSelf-administered fentanyl profoundly impacts rat brain innate immune targets
External LinkCatecholamine signaling that modulates cerebellar operations in cognition
External LinkMachine-learning approaches to classify and understand emotion states in mice
External LinkApplied natural language processing in mental health big data
External LinkLinking cell types to behavior in the vertebrate hypothalamus
External LinkGWAS meets transcriptomics: from genetic letters to transcriptomic words of neuropsychiatric risk
External LinkPlasma psilocin critically determines behavioral and neurobiological effects of psilocybin
External LinkSerotonin minting new mitochondria in cortical neurons: implications for psychopathology
External LinkBetter living through chemistry: MDMA’s prosocial mechanism as a starting point for improved therapeutics
External LinkNIDA vision for big data science to understand the biological underpinnings of substance use disorders
External LinkUsing the exposome to understand environmental contributors to psychiatric disorders
External LinkOpioids and maternal brain–behavior adaptation
External LinkHabenular TCF7L2 links nicotine addiction to diabetes: the broad significance
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Volume Fifteen - Prefrontal Cortex
Editorials
The prefrontal cortex
External LinkReviews
Evolution of prefrontal cortex
External LinkPrefrontal connectomics: from anatomy to human imaging
External LinkDevelopment of prefrontal cortex
External LinkComputational models of adaptive behavior and prefrontal cortex
External LinkThe role of prefrontal cortex in cognitive control and executive function
External LinkThe role of PFC networks in cognitive control and executive function
External LinkAdvances in modeling learning and decision-making in neuroscience
External LinkThe prefrontal cortex and (uniquely) human cooperation: a comparative perspective
External LinkForaging with the frontal cortex: A cross-species evaluation of reward-guided behavior
External LinkReinforcement-learning in fronto-striatal circuits
External LinkPrefrontal cortex and depression
External LinkPrefrontal cortex interactions with the amygdala in primates
External LinkThe prefrontal cortex and OCD
External LinkInteractions between ventrolateral prefrontal and anterior cingulate cortex during learning and behavioural change
External LinkPrefrontal-hippocampal interactions supporting the extinction of emotional memories: the retrieval stopping model
External LinkPrefrontal cortex, amygdala, and threat processing: implications for PTSD
External LinkThe prefrontal cortex, pathological anxiety, and anxiety disorders
External LinkThe neurobiology of drug addiction: cross-species insights into the dysfunction and recovery of the prefrontal cortex
External LinkMechanisms underlying dorsolateral prefrontal cortex contributions to cognitive dysfunction in schizophrenia
External LinkNeuromodulation of prefrontal cortex cognitive function in primates: the powerful roles of monoamines and acetylcholine
External LinkPrefrontal contributions to the stability and variability of thought and conscious experience
External LinkThe prefrontal cortex and neurosurgical treatment for intractable OCD
External LinkNoninvasive neuromodulation of the prefrontal cortex in mental health disorders
External LinkHot Topics
Recent findings on the role of sensory and interoceptive-related circuits in relapse to drug seeking
External LinkPFC neuromodulation with theta burst stimulation to impact behavior and neural network activity in schizophrenia and bipolar disorder
External LinkThinner cortices in high-risk offspring: the promises of big data
External LinkIdentifying subtypes of PTSD to promote precision medicine
External LinkFirst in vivo evaluations of synaptic density alterations in the brain
External LinkNew myelin for old memories
External LinkThe paraventricular nucleus of the thalamus and its potential role in psychopathology
External LinkMicroRNAs as promising peripheral sensors of prefrontal cortex developmental trajectory and psychiatric risk
External LinkDeveloping breakthrough psychiatric treatments by modulating G protein-coupled receptors on prefrontal cortex somatostatin interneurons
External LinkSuper glue: emerging roles for non-neuronal brain cells in mental health
External LinkBrain-enriched CACNA1C isoforms as novel, selective targets for psychiatric indications
External LinkDensely sampled neuroimaging for maximizing clinical insight in psychiatric and addiction disorders
External LinkOrexin modulation of stress reactivity as a novel targeted treatment for anxiety and alcohol use disorder
External LinkNovel approaches to estimate prefrontal synaptic strength in vivo in humans: of relevance to depression, schizophrenia, and ketamine
External Link“Archealization” of human brain organoids
External LinkLeveraging resting-state neurophenotypes to identify susceptibility to and heterogeneity of posttraumatic stress disorder
External LinkDisease-modifying pharmacological approaches to correcting basal forebrain cholinergic neuronal (BFCN) dysfunction and degeneration
External LinkBrain sex differences: the androgynous brain is advantageous for mental health and well-being
External LinkThe prenatal environment and risk for mental illness in young people
External LinkMobile DNA and the brain
External LinkThe evolution of the psychedelic revolution
External LinkMapping causal generators of appetitive motivation-hedonic functions in frontal cortex
External Link“Neuroanatomical integration of homeostatic and hedonic brain regions to regulate consummatory behavior”
External LinkAcute effects of a high-fat diet on estrous cycling and body weight of intact female mice
External LinkIdentifying novel mechanisms and treatment targets for irritability and aggression in psychiatric disorders
External LinkPrecision medicine in psychiatry: biomarkers to the forefront
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Volume Sixteen - Synaptic plasticity as a therapeutic target to modulate circuits in psychiatric disorders
Editorials
Synaptic plasticity as a therapeutic target to modulate circuits in psychiatric disorders
External LinkReviews
Net gain and loss: influence of natural rewards and drugs of abuse on perineuronal nets
External LinkAstrocyte regulation of synaptic signaling in psychiatric disorders
External LinkEndocannabinoids at the synapse and beyond: implications for neuropsychiatric disease pathophysiology and treatment
External LinkRapid homeostatic plasticity and neuropsychiatric therapeutics
External LinkSleep-mediated regulation of reward circuits: implications in substance use disorders
External LinkNeural circuits regulating prosocial behaviors
External LinkPlasticity of synapses and reward circuit function in the genesis and treatment of depression
External LinkTowards an understanding of psychedelic-induced neuroplasticity
External LinkSynaptic plasticity and mental health: methods, challenges and opportunities
External LinkAdaptive control of synaptic plasticity integrates micro- and macroscopic network function
External LinkSustained effects of single doses of classical psychedelics in humans
External LinkNeuroimaging in schizophrenia: an overview of findings and their implications for synaptic changes
External LinkPsychosis spectrum illnesses as disorders of prefrontal critical period plasticity
External LinkImaging synaptic density in depression
External LinkAssessing the mechanisms of brain plasticity by transcranial magnetic stimulation
External LinkHot Topics
Using metabolic imaging to investigate neuromodulatory mechanisms of rTMS
External LinkSchrooms against booze: Potential of mycotherapy for the treatment of AUD
External LinkNeurotrophic effects of potentiating gaba-mediated dendritic inhibition
External LinkDoes the trip matter? Investigating the role of the subjective effects of psychedelics in persisting therapeutic effects
External LinkProbing long-term potentiation-like visual cortical plasticity in humans using repeated visual stimulation: effects on visual evoked potentials
External LinkNeuroimaging of plasticity mechanisms in the human brain: from critical periods to psychiatric conditions
External LinkN6-methyladenosine (m6A) epitranscriptomics in synaptic plasticity and behaviors
External LinkPlasticity markers in the human brain associated with rapid antidepressants
External LinkThe role of racial discrimination in dissociation and interoceptive dysfunction
External LinkSleep disturbance in substance use disorders: the orexin (hypocretin) system as an emerging pharmacological target
External LinkThe double-edged sword of the double-stranded break
External LinkBeyond the hypothalamus: roles for insulin as a regulator of neurotransmission, motivation, and feeding
External LinkUnexpected circuit-level tradeoffs in human stress resilience
External LinkEchoes of ancient DNA in living modern humans affect risk for neuropsychiatric disease and brain structure and function of networks subserving higher-order cognition
External LinkReal-time fMRI neurofeedback: the promising potential of brain-training technology to advance clinical neuroscience
External LinkShaping long-range functional connectivity through prefrontal interneuron plasticity
External LinkSingle-cell transcriptional profiling in brain reward structures
External LinkBlood-based biomarkers for suicide in depression: moving a step closer to prediction
External LinkEpigenetic aging in psychiatry: clinical implications and therapeutic opportunities
External LinkHow much is too much? New evidence associating low levels of prenatal alcohol exposure with brain differences in children
External LinkReaching for the unreachable: low intensity focused ultrasound for non-invasive deep brain stimulation
External LinkTargeted and transient opening of the blood brain barrier in discrete neurocircuits and brain regions
External LinkThe promise of 3,4-methylenedioxymethamphetamine (MDMA) in combination with prolonged exposure therapy for posttraumatic stress disorder
External LinkSynaptic plasticity of the orbitofrontal cortex in obesity
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Volume Seventeen - Rapid and Novel Treatments in Psychiatry
Editorials
Rapid and novel treatments in psychiatry: the future is now
External LinkPerspectives
Finding new and better treatments for psychiatric disorders
External LinkNo time to lose: the current state of research in rapid-acting psychotherapeutics
External LinkThe Brain & Behavior Research Foundation’s philanthropic support for neuropsychiatric research
External LinkNavigating the FDA regulatory landscape
External LinkAre novel treatments for brain disorders hiding in plain sight?
External LinkPharmacogenomic testing for antidepressant treatment selection: lessons learned and roadmap forward
External LinkElectronic health records and stratified psychiatry: bridge to precision treatment?
External LinkEthical considerations in rapid and novel treatments in psychiatry
External LinkEnsuring psychedelic treatments and research do not leave anyone behind
External LinkReviews
Ketamine in neuropsychiatric disorders: an update
External LinkKetamine and rapid antidepressant action: new treatments and novel synaptic signaling mechanisms
External LinkTherapeutic potential of N-methyl-D-aspartate receptor modulators in psychiatry
External LinkNovel neurosteroid therapeutics for post-partum depression: perspectives on clinical trials, program development, active research, and future directions
External LinkNeurosteroids: mechanistic considerations and clinical prospects
External LinkModulators of GABAA receptor-mediated inhibition in the treatment of neuropsychiatric disorders: past, present, and future
External LinkPsychedelic therapies reconsidered: compounds, clinical indications, and cautious optimism
External LinkTherapeutic mechanisms of psychedelics and entactogens
External LinkPsychedelics: preclinical insights provide directions for future research
External LinkAccelerated TMS - moving quickly into the future of depression treatment
External LinkClosing the loop in psychiatric deep brain stimulation: physiology, psychometrics, and plasticity
External LinkHow electroconvulsive therapy works in the treatment of depression: is it the seizure, the electricity, or both?
External LinkClosed-loop neurostimulation for the treatment of psychiatric disorders
External LinkThe future of brain circuit-targeted therapeutics
External LinkThe why, when, where, how, and so what of so-called rapidly acting antidepressants
External LinkHow should we design future mechanistic and/or efficacy clinical trials?
External LinkDigital and precision clinical trials: innovations for testing mental health medications, devices, and psychosocial treatments
External LinkAdvancing preclinical chronic stress models to promote therapeutic discovery for human stress disorders
External LinkThe role of neurotrophic factors in novel, rapid psychiatric treatments
External LinkAntidepressants enter cells, organelles, and membranes
External LinkNovel mechanism-based treatments for pediatric anxiety and depressive disorders
External LinkHot Topics
Cell type specific focused ultrasound neuromodulation in preclinical models of sleep and psychiatric disorders
External LinkDisassociating drug active ingredients from inactive: ketamine-like synaptic effects of a ketamine excipient
External LinkUnraveling the cell-type-specific molecular pathways of PTSD: integrating GWAS with brain genomic profiling and in vitro modeling
External LinkPotential applications of temporal interference deep brain stimulation for the treatment of transdiagnostic conditions in psychiatry
External LinkKynurenic acid: translational perspectives of a therapeutically targetable gliotransmitter
External LinkNeurobiology and treatment advances for prolonged grief disorder
External LinkA novel rat model of potentiated incubation of opioid craving after abstinence induced by adverse consequences of drug seeking
External LinkHerpesviruses and neuropsychiatric disorders: overlooked adversaries or innocent bystanders?
External LinkExploring the role of mu opioid receptors in the therapeutic potential and abuse liability of (S)-ketamine
External LinkRepurposing anti-inflammatory medications for alcohol and substance use disorders
External LinkIntegrating public health and translational basic science to address challenges of xylazine adulteration of fentanyl
External LinkA path to novel, effective treatments for schizophrenia
External LinkMoving beyond descriptive nosology: an argument for negative valence systems disorder
External LinkFrom high-throughput transcriptome characterization of individual synaptosomes to constructing the whole-brain connectome
External LinkSwell1 channel-mediated tonic GABA release from astrocytes modulates cocaine reward
External LinkThe orexin neurotransmitter system as a target for medication development for opioid use disorder
External LinkA unique role for cAMP signaling in microglia during opioid tolerance and withdrawal
External LinkEpigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid overdose
External LinkLeveraging AI to predict substance use disorder treatment outcomes
External LinkThe biological embedding of structural inequities: new insight from neuroscience
External LinkPotentiation of AMPA receptors for rapid therapeutic gain in psychiatry has reached a new level of excitement
External LinkCentral amygdala CRF1 cells control nociception and anxiety-like behavior
External LinkGene–brain–behavior mechanisms underlying autism spectrum disorder: implications for precision psychiatry
External LinkMicrobes and mental health: translating preclinical findings to the clinic
External LinkTowards personalized medicine: subtyping using functional profiles
External LinkPostmortem-derived iPSC models in substance use disorders research
External LinkTranscranial focused ultrasound (tFUS): a promising noninvasive deep brain stimulation approach for pain
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