Editorials

The prefrontal cortex

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Suzanne N. Haber & Trevor Robbins

Reviews

Evolution of prefrontal cortex

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Todd M. Preuss & Steven P. Wise

Prefrontal connectomics: from anatomy to human imaging

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Suzanne N. Haber, Hesheng Liu, Jakob Seidlitz & Ed Bullmore

Development of prefrontal cortex

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Sharon M. Kolk & Pasko Rakic

Computational models of adaptive behavior and prefrontal cortex

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Alireza Soltani & Etienne Koechlin

The role of prefrontal cortex in cognitive control and executive function

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Naomi P. Friedman & Trevor W. Robbins

The role of PFC networks in cognitive control and executive function

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Vinod Menon & Mark D’Esposito

Advances in modeling learning and decision-making in neuroscience

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Anne G. E. Collins & Amitai Shenhav

The prefrontal cortex and (uniquely) human cooperation: a comparative perspective

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Yoonseo Zoh, Steve W. C. Chang & Molly J. Crockett

Foraging with the frontal cortex: A cross-species evaluation of reward-guided behavior

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Peter H. Rudebeck & Alicia Izquierdo

Reinforcement-learning in fronto-striatal circuits

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Bruno Averbeck & John P. O’Doherty

Prefrontal cortex and depression

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Diego A. Pizzagalli & Angela C. Roberts

Prefrontal cortex interactions with the amygdala in primates

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Elisabeth A. Murray & Lesley K. Fellows

The prefrontal cortex and OCD

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Susanne E. Ahmari & Scott L. Rauch

Interactions between ventrolateral prefrontal and anterior cingulate cortex during learning and behavioural change

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Ilya E. Monosov & Matthew F. S. Rushworth

Prefrontal-hippocampal interactions supporting the extinction of emotional memories: the retrieval stopping model

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Michael C. Anderson & Stan B. Floresco

Prefrontal cortex, amygdala, and threat processing: implications for PTSD

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M. Alexandra Kredlow, Robert J. Fenster, Emma S. Laurent, Kerry J. Ressler & Elizabeth A. Phelps

The prefrontal cortex, pathological anxiety, and anxiety disorders

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Margaux M. Kenwood, Ned H. Kalin & Helen Barbas

The neurobiology of drug addiction: cross-species insights into the dysfunction and recovery of the prefrontal cortex

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Ahmet O. Ceceli, Charles W. Bradberry & Rita Z. Goldstein

Mechanisms underlying dorsolateral prefrontal cortex contributions to cognitive dysfunction in schizophrenia

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Jason Smucny, Samuel J. Dienel, David A. Lewis & Cameron S. Carter

Neuromodulation of prefrontal cortex cognitive function in primates: the powerful roles of monoamines and acetylcholine

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Roshan Cools & Amy F. T. Arnsten

Prefrontal contributions to the stability and variability of thought and conscious experience

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Andre Zamani, Robin Carhart-Harris & Kalina Christoff

The prefrontal cortex and neurosurgical treatment for intractable OCD

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Steven A. Rasmussen & Wayne K. Goodman

Noninvasive neuromodulation of the prefrontal cortex in mental health disorders

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William T. Regenold, Zhi-De Deng & Sarah H. Lisanby

Hot Topics

Recent findings on the role of sensory and interoceptive-related circuits in relapse to drug seeking

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David J. Reiner & Yavin Shaham

PFC neuromodulation with theta burst stimulation to impact behavior and neural network activity in schizophrenia and bipolar disorder

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Fabio Ferrarelli & Mary L. Phillips

Thinner cortices in high-risk offspring: the promises of big data

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Myrna M. Weissman & Ardesheer Talati

Identifying subtypes of PTSD to promote precision medicine

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Carole Siegel & Eugene Laska

First in vivo evaluations of synaptic density alterations in the brain

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Irina Esterlis & Sophie Holmes

New myelin for old memories

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Michael C. Kern & Mazen A. Kheirbek

The paraventricular nucleus of the thalamus and its potential role in psychopathology

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Shelly B. Flagel

MicroRNAs as promising peripheral sensors of prefrontal cortex developmental trajectory and psychiatric risk

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Alice Morgunova & Cecilia Flores

Developing breakthrough psychiatric treatments by modulating G protein-coupled receptors on prefrontal cortex somatostatin interneurons

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Nicole A. Crowley & Max E. Joffe

Super glue: emerging roles for non-neuronal brain cells in mental health

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William A. Carlezon Jr & Galen Missig

Brain-enriched CACNA1C isoforms as novel, selective targets for psychiatric indications

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Nicola A. L. Hall & Elizabeth M. Tunbridge

Densely sampled neuroimaging for maximizing clinical insight in psychiatric and addiction disorders

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Sarah W. Yip & Anna B. Konova

Orexin modulation of stress reactivity as a novel targeted treatment for anxiety and alcohol use disorder

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Stephanie M. Gorka & K. Luan Phan

Novel approaches to estimate prefrontal synaptic strength in vivo in humans: of relevance to depression, schizophrenia, and ketamine

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Chadi G. Abdallah & Graeme F. Mason

“Archealization” of human brain organoids

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Alysson R. Muotri

Leveraging resting-state neurophenotypes to identify susceptibility to and heterogeneity of posttraumatic stress disorder

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Nathaniel G. Harnett & Lauren A. M. Lebois

Disease-modifying pharmacological approaches to correcting basal forebrain cholinergic neuronal (BFCN) dysfunction and degeneration

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John J. Alam & Ralph A. Nixon

Brain sex differences: the androgynous brain is advantageous for mental health and well-being

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Qiang Luo & Barbara J. Sahakian

The prenatal environment and risk for mental illness in young people

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Joshua L. Roffman & Erin C. Dunn

Mobile DNA and the brain

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Amy C. Lossie & Jonathan D. Pollock

The evolution of the psychedelic revolution

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Lindsay P. Cameron & David E. Olson

Mapping causal generators of appetitive motivation-hedonic functions in frontal cortex

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Brian A. Baldo & Kent C. Berridge

“Neuroanatomical integration of homeostatic and hedonic brain regions to regulate consummatory behavior”

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Ashley E. Smith & Jonathan D. Hommel

Acute effects of a high-fat diet on estrous cycling and body weight of intact female mice

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Melissa E. Lenert & Michael D. Burton

Identifying novel mechanisms and treatment targets for irritability and aggression in psychiatric disorders

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Manish Kumar Jha & Madhukar H. Trivedi

Precision medicine in psychiatry: biomarkers to the forefront

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Alexander B. Niculescu & Helen Le-Niculescu