Addiction as a brain disease revised: why it still matters, and the need for consilience

Addiction as a brain disease revised: why it still matters, and the need for consilience Big data in psychiatry: multiomics, neuroimaging, computational modeling, and digital phenotyping Acute dose-dependent effects of lysergic acid diethylamide in a double-blind placebo-controlled study in healthy subjects. Big behavior: challenges and opportunities in a new era of deep behavior profiling. Leveraging large genomic datasets to illuminate the pathobiology of autism spectrum disorders Pubertal adversity alters chromatin dynamics and stress circuitry in the pregnant brain. Social networking and mental health: looking beyond frequency of use and towards mechanisms of action. Distinct acute effects of LSD, MDMA, and D-amphetamine in healthy subjects. Chronic opioid pretreatment potentiates the sensitization of fear learning by trauma. Intra-individual changes in methylome profiles: an epigenetic ‘scar’ of early-life adversity?