Volume Five



Table of Contents


Gwenn S Smith, Xiaohua Li and P Jeffrey Conn

From Revolution to Evolution: The Glutamate Hypothesis of Schizophrenia and its Implication for Treatment

Muscarinic and Nicotinic Acetylcholine Receptor Agonists and Allosteric Modulators for the Treatment of Schizophrenia

Cognitive Training for Impaired Neural Systems in Neuropsychiatric Illness

Review of Pharmacological Treatment in Mood Disorders and Future Directions for Drug Development

Somatic Treatments for Mood Disorders

Cognitive Mechanisms of Treatment in Depression

Psychoneuroimmunology Meets Neuropsychopharmacology: Translational Implications of the Impact of Inflammation on Behavior

Novel Therapeutic Strategies for Alcohol and Drug Addiction: Focus on GABA, Ion Channels and Transcranial Magnetic Stimulation

Therapeutic Strategies in Fragile X Syndrome: Dysregulated mGluR Signaling and Beyond

Networking in Autism: Leveraging Genetic, Biomarker and Model System Findings in the Search for New Treatments

Parkinson's Disease Therapeutics: New Developments and Challenges Since the Introduction of Levodopa

Epigenetic Treatments for Cognitive Impairments

Alzheimer's Therapeutics: Translation of Preclinical Science to Clinical Drug Development


New Era for Novel CNS Drug Development

Translating Discoveries into Medicine: Psychiatric Drug Development in 2011

NIA Commentary: Translational Issues in Alzheimer's Disease Drug Development

Neuroscience Networking: Linking Discovery to Drugs

New Medications for Substance Use Disorders: Challenges and Opportunities

The Role of Complementary, Alternative, and Integrative Medicine in Personalized Health Care

Hot Topics

Grateful DREADDs: Engineered Receptors Reveal How Neural Circuits Regulate Behavior

Dopamine D3 Receptor Function and Cocaine Exposure

Chronic N-acetylcysteine after cocaine self-administration produces enduring reductions in drug-seeking

Methamphetamine-Induced Oxidation of Proteins and Alterations in Protein Processing

Placental Source for 5-HT that Tunes Fetal Brain Development

Mainstreaming Mice

Phospholipase D as a Therapeutic Target in Brain Disorders

Transferrin Antibodies Into the Brain

Endogenous Opioids as Physiological Antidepressants: Complementary Role of Delta Receptors and Dopamine

Oxytocin as a Potential Therapeutic Target for Schizophrenia and Other Neuropsychiatric Conditions

Dysregulation of mTOR Signaling in Neuropsychiatric Disorders: Therapeutic Implications

Habenular Signaling in Nicotine Reinforcement

Circuits, Cells, and Synapses: Toward a New Target for Deep Brain Stimulation in Depression

Update on Corticotropin-Releasing Factor Pharmacotherapy for Psychiatric Disorders: A Revisionist View

Update on Omega-3 Polyunsaturated Fatty Acids in Early-Stage Psychotic Disorders

Beyond Antipsychotics: Pharmacologically-Augmented Cognitive Therapies (PACTs) for Schizophrenia

From Father to Offspring: Paternal Transmission of Depressive-Like Behaviors

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