Anatomic and Functional Brain Imaging in Alzheimer's Disease / Table 6

TABLE 6. Spearman rank-sum correlations between visuospatial-verbal neuropsychological discrepancies and right-left metabolic asymmetries in AD patients when initially mildly demented and at last evaluation^a-c

	^{Cerebral metabolic asymmetry}
Neuropsychological discrepancy	Prefrontal	Premotor	Parietal	Lat temporal
Controls
WAIS PDQ minus MDQ (N = 29)	- 0.07	- 0.06	0.02	0.03
Visual minus verbal recall (N = 15)	- 0.30	- 0.39	- 0.40	- 0.17

Mild AD (N = 10)
Initial evaluation
WAIS PDQ minus MDQ Visual minus verbal recall	0.04 -0.22	- 0.09 -0.21	- 0.16 -0.16	0.04 -0.18

Last evaluation
WASI PDQ minus MDQ	0.78 ^{* *}	0.67 *	0.50	0.59
Visual minus verbal recall	0.44	0.41	0.68 *	0.71 *

^aFrom ref. 31.

^bWAIS, Wechsler Adult Intelligence Scale; PDQ, perceptual organization deviation quotient; MDQ, memory and freedom from distractibility quotient.

^c Statistically significant:* * p < 0.01; * p < 0.05.

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