TABLE 5.  Annual rates of change for instruments used to assess cognitive function in Alzheimer’s disease

 

Instrument

 

Range

 

Reference

 

N

Annual

change

 

S.D.

 

 

62

120

2.2

5.0

MMSE

0-30

59

106

2.8

4.6

 

 

41

430

3.9

3.7

BIMC

0-33

53

213

4.1

4.1

 

 

28

161

4.4

3.6

ADAS-Cog

0-70

54

253

9.6

8.2

Mattis Scale

0-144

51

55

11.4

11.1

CERAD Battery

 

41

 

 

 

Word list

0-30

 

430

2.0

2.4

Naming

0-15

 

430

2.0

2.2

Drawings

0-11

 

428

1.3

1.9

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published 2000