Pharmacologic

subtype:

M1

M2

M3

M4

-

Molecular subtype:

m1

m2

m3

m4

m5

Some relatively

selective

antagonists:

Pirenzepine

-

-

-

-

Principal regions of

Brain

Heart

Exocrine glands

Brain

Brain

expression:

Exocrine glands

Smooth muscle

Brain

Brain

Smooth muscle

Major biochemical

Inositol phosphate

Inhibit cyclic

Inositol phosphate

Inhibit cyclic

Inositol phosphate

response:

release

AMP

release

AMP

release