Anatomic and Functional Brain Imaging in Alzheimer's Disease / Table 3

TABLE 3. Right-left metabolic asymmetries [Eq. (1)] in control subjects and in AD patients of differing dementia severity^a,b

	Right-left metabolic asymmetries
Brain regions	Controls (31)	Mild AD (11)	Moderate AD (13)	Severe AD (8)
Association cortex
Perfrontal	0.01 ± 0.03	-0.01 ± 0.07^*	-0.01 ± 0.08^***	0.05 ± 0.10^***
Premotor	0.01 ± 0.05	-0.01 ± 0.10^**	-0.02 ± 0.16^***	0.05 ± 0.11^**
Orbitofrontal	-0.01 ± 0.06	-0.03 ± 0.08	-0.03 ± 0.11^**	0.00 ± 0.11^*
Parietal	-0.01 ± 0.06	-0.01 ± 0.11^*	-0.03 ± 0.13^*	0.08 ± 0.13^*
Lateral temporal	-0.01 ± 0.07	-0.05 ± 0.17^**	-0.03 ± 0.18^***	0.08 ± 0.23^***

Primary cortex
Sensorimotor	-0.02 ± 0.05	-0.01 ± 0.07	0.00 ± 0.06	0.01 ± 0.08
Occipital^c	-0.01 ± 0.04	0.00 ± 0.05	-0.01 ± 0.03	0.03 ± 0.08^*

^a Values are means ± SD (number of subjects). Scanditronix PC 1024-7B data from ref. 31.

^bVariance greater than in controls: ^* p < 0.05; ^** p < 0.01; ^*** p < 0.001.

^c Primary and unimodal association cortex.