FIG. 1

Annual rate of cognitive change (ARCC) scores obtained from Alzheimer patients in a longitudinal study. Squares representing mean change scores on the cognitive portion of the Alzheimer's Disease Assessment Scale (cADAS) are shown as a function of the baseline score (base). Triangles represent predicted values calculated from the quadratic equation fit by the method of least squares to the original 253 annual change scores: ARCC = -6.357 + 1.022 {ewc MVIMG, MVIMAGE,!times.bmp} base - 0.01339 {ewc MVIMG, MVIMAGE,!times.bmp} base2 (R = 0.42, F = 27.46, df = 2250, p < .001). Straight lines connecting the estimated points approximate the actual quadratic equation. (From ref. 54, with permission. Copyright 1994, American Psychiatric Association.)

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published 2000