Figure 4b.

Escalating doses of haloperidol in a healthy volunteer. Each panel represent four slices within the basal ganglia, acquired on separate days. Top left, baseline placebo; top right, after the administration of 1 mg haloperidol; bottom left, after 2.5 mg; bottom right, after 5 mg. Note that the increased dose of haloperidol is associated with decreased specific activity in the basal ganglia, reflecting increased competition. (Illustration courtesy of Abass Alavi, MD, Hank Kung, PhD, and P David Mozley, MD, Department of Radiology, University of Pennsylvania)

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published 2000