TABLE 3. Prenatal influenza and adult schizophrenia | ||
Study | Sample | Findingsa |
Mednick et al. (50) | pregnancies coincident with
Helsinki 1957
A-2 epidemic |
{ewc MVIMG,
MVIMAGE,!uparrow.BMP} in schizophrenia in second-trimester cohort,
especially at 6th months' gestation |
Kendell and Kemp
(42) |
pregnancies coincident with
Scottish
1918, 1991, and 1957 A-2 epidemics |
{ewc MVIMG,
MVIMAGE,!uparrow.BMP} in Edinburgh samples for 1957, second
trimester. No {ewc MVIMG, MVIMAGE,!uparrow.BMP} association in entire sample |
Torrey et al. (65) | 43,814 schizophrenic births
between
1950-1959 in USA |
No {ewc MVIMG, MVIMAGE,!uparrow.BMP} in association with 1957 A-2 |
Barr et al. (7) | Danish schizophrenic samples
born
between 1911 and 1950 ( N = 7239 ) |
{ewc MVIMG,
MVIMAGE,!uparrow.BMP} in schizophrenia in 6 to 7-month gestational
group coincident with high incidence of influenza compared with group coincident with low incidence |
O'Callaghan et al.
(53) |
339 schizophrenic patients
born around
English 1957 A-2 epidemic |
abnormal distribution of schizophrenia
births
in index year in women only, appearance of {ewc MVIMG, MVIMAGE,!uparrow.BMP} in risk in 5th gestational month |
Sham et al. (59) | British Hospital First Admission
between
1970-1979 with schizophrenia, N not specified |
weak statistical association
between
frequency patern of influenza deaths between 1939 and 1960 and second trimester of schizophrenic births |
Crow and Done
(21) |
1620 pregnancies with history
of 1957 A-
2 influenza infection in Great Britain |
no increased risk of schizophrenia |
a {ewc MVIMG, MVIMAGE,!uparrow.BMP}, increase.
published 2000