1. Abernethy DR, Greenblatt DJ, Shader RI. Imipramine disposition in users of oral contraceptive steroids. Clin Pharmacol Ther 1984;35(6):792–797.

2. Agosti V, Stewart JW, Quitkin FM. Life satisfaction and psychosocial functioning in chronic depression: effect of acute treatment with antidepressants. J Affect Dis 1991;23:35–41.

3. Akiskal HS. Factors associated with incomplete recovery in primary depressive illness. J Clin Psychiatry 1982;43:266–271.

4. American Psychiatric Association. Practice guideline for major depressive disorder in adults. Am J Psychiatry 1993;150(4, Suppl):4–26.

5. Anthony JC, Helzer JE. Syndromes of drug abuse and dependence. In: Robins LN, Regier DA, eds. Psychiatric disorders in America. New York: The Free Press; 1991:116–154.

6. Billings A, Moos R. Psychosocial theory and research on depression: an integrative framework and review. Clin Psychol Rev 1982;2:213–237.

7. Bottiger LE, Furhoff AK, Holmberg L. Fatal reactions to drugs. Acta Med Scand 1979;205:451–456.

8. Brodaty H, Peters K, Boyce P, et al. Age and depression. J Affect Dis 1991;23(3):137–149.

9. Brown RP, Sweeney J, Frances A, Kocsis JH, Loutsch E. Age as a predictor of treatment response in endogenous depression. J Clin Psychopharmacol 1983;3:176–178.

10. Bruce ML, Takeuchi DT, Leaf PJ. Poverty and psychiatric status. Arch Gen Psychiatry 1991;48:470–474.

11. Brugha TS, Bebbington PE, MacCarthy B, Sturt E, Wykes T, Potter J. Gender, social support and recovery from depressive disorders: a prospective clinical study. Psychol Med 1990;20:147–156.

12. Clayton PJ. Gender and depression. In: Angst J, ed. The origins of depression: current concepts and approaches. New York: Springer-Verlag; 1983:77–89.

13. Clayton PJ. The comorbidity factor: establishing the primary diagnosis in patients with mixed symptoms of anxiety and depression. J Clin Psychiatry 1990;51(11, Suppl):35–39.

14. Clayton PJ, Grove WM, Coryell W, Keller M, Hirschfeld RMA, Fawcett J. Follow-up and family study of anxious depression. Am J Psychiatry 1991;148(11):1512–1517.

15. Clayton P, Halikes J, Mauvie W. The bereavement of the widow. Dis Nerv Syst 1974;32:597–604.

16. Coryell W, Endicott J, Keller M. Outcome of patients with chronic affective disorder: a five-year follow-up. Am J Psychiatry 1990;147:1627–1633.

17. Coryell W, Endicott J, Keller M. Major depression in a nonclinical sample. Demographic and clinical risk factors for first onset. Arch Gen Psychiatry 1992;49:117–125.

18. Coryell W, Scheftner W, Keller M, Endicott J, Maser J, Klerman GL. The enduring psychosocial consequences of mania and depression. Am J Psychiatry 1993;150(5):720–727.

19. Croughan JL, Secunda SK, Katz MM, et al. Sociodemographic and prior clinical course characteristics associated with treatment response in depressed patients. J Psychiatr Res 1988;22(3):227–237.

20. Davidson J, Miller R, Strickland R. Neuroticism and personality disorder in depression. J Affect Dis 1985;8:177–182.

21. Davidson J, Pelton S. Forms of atypical depression and their response to antidepressant drugs. Psychiatry Res 1986;17:87–95.

22. Flaherty JA, Gaviria FM, Black EM, Altman E, Mitchell T. The role of social support in the functioning of patients with unipolar depression. Am J Psychiatry 1983;140(4):473–476.

23. Giller E Jr, Bialos D, Riddle MA, Waldo MC. MAOI treatment response: multiaxial assessment. J Affect Dis 1988;14:171–175.

24. Hamilton JA, Alagna SW, Pinkel S. Gender differences in antidepressant and activating drug effects on self-perceptions. J Affect Dis 1984;7:235–243.

25. Helzer JE, Burnam A, McEvoy LT. Alcohol abuse and dependence. In: Robins LN, Regier DA, eds. Psychiatric disorders in America. New York: The Free Press; 1991:81–115.

26. Hirschfeld RMA, Klerman GL, Clayton PJ, Keller MB. Personality and depression. Arch Gen Psychiatry 1983;40:993–998.

27. Hirschfeld RMA, Klerman GL, Lavori P, Keller MB, Griffith P, Coryell W. Premorbid personality assessments of first onset of major depression. Arch Gen Psychiatry 1989;46:345–350.

28. Hirschfeld RMA, Shea MT. Personality. In: Paykel ES, ed. Handbook of affective disorders. New York: Churchill-Livingstone; 1992:185–194.

29. Hooley JM, Orley J, Teasdale JD. Levels of expressed emotion and relapse in depressed patients. Br J Psychiatry 1986;148:642–647.

30. Hooley JM, Teasdale JD. Predictors of relapse in unipolar depressives: expressed emotion, marital distress, and perceived criticism. J Abnorm Psychol 1989;98:229–235.

31. Hunt N, Bruce-Jones W, Silverstone T. Life events and relapse in bipolar affective disorder. J Affect Dis 1992;25(1):13–20.

32. Jacobs SC, Nelson JC, Zisook S. Treating depressions of bereavement with antidepressants. Psychiatr Clin North Am 1987;10(3): 501–510.

33. Joyce PR. Prediction of treatment response. In: Paykel ES, ed. Handbook of affective disorders. New York: Churchill-Livingstone; 1992:453–462.

34. Keitner GI, Ryan CE, Miller IW, Norman WH. Recovery and major depression: factors associated with twelve-month outcome. Am J Psychiatry 1992;149(1):93–99.

35. Keller MB, Klerman GL, Lavori PW, Coryell W, Endicott J, Taylor J. Long-term outcome of episodes of major depression: clinical and public health significance. JAMA 1984;252:788–792.

36. Keller MB, Lavori PW, Rice J, Coryell W, Hirschfeld RMA. The persistent risk of chronicity in recurrent episodes of nonbipolar major depressive disorder: a prospective follow-up. Am J Psychiatry 1986;143(1):24–28.

37. Keller MB, Shapiro RW, Lavori PW, Wolfe N. Recovery in major depressive disorder. Arch Gen Psychiatry 1982;39:905–910.

38. Keller MB, Shapiro RW, Lavori PW, Wolfe N. Relapse in major depressive disorder. Arch Gen Psychiatry 1982;39:911–915.

39. Klerman GL, Lavori PW, Rick J, et al. Birth-cohort trends in rates of major depressive disorder among relatives of patients with affective disorder. Arch Gen Psychiatry 1985;42:689–693.

40. Kocsis JH, Sutton BM, Frances AJ. Long-term follow-up of chronic depression treated with imipramine. J Clin Psychiatry 1991;52(2): 56–59.

41. Lewinsohn PM, Fenn DS, Stanton AK, Franklin J. Relation of age at onset to duration of episode in unipolar depression. Psychol Aging 1986;1:63–68.

42. Liebowitz MR. Depression with anxiety and atypical depression. J Clin Psychiatry 1993;54(2, Suppl):10–14.

43. Lloyd C. Life events and depressive disorders reviewed. 2. Events as precipitating factors. Arch Gen Psychiatry 1980;37:541–548.

44. Maier W, Lichtermann D, Minges J, Heun R. Personality traits in subjects at risk for unipolar major depression: a family study perspective. J Affect Dis 1992;24(3):153–163.

45. Maj M, Del-Vecchio M, Starace F, Pirozzi R, Kemali D. Prediction of affective psychoses responses to lithium prophylaxis: the role of sociodemographic, clinical, psychological and biological variables. Acta Psychiatr Scand 1984;69:37–44.

46. Markowitz JS, Weissman MM, Ouellette R, Lish JD, Klerman GL. Quality of life in panic disorder. Arch Gen Psychiatry 1989;46:984–992.

47. McLeod JD, Kessler RC, Landis KR. Speed of recovery from major depressive episodes in a community sample of married men and women. J Abnorm Psychol 1992;101(2):277–286.

48. Miklowitz DJ, Goldstein MJ, Nuechterlein KH, Snyder KS, Mintz J. Family factors and the course of bipolar affective disorder. Arch Gen Psychiatry 1988;45:225–231.

49. Miller IW, Keitner GI, Whisman MA, Ryan CE, Epstein NB, Bishop DS. Depressed patients with dysfunctional families: description and course of illness. J Abnorm Psychol 1992;101(4):637–646.

50. Murphy JM, Oliver DC, Monson RR, Sobol AM, Federman EB, Leighton AH. Depression and anxiety in relation to social status. Arch Gen Psychiatry 1991;48:223–229.

51. Needles DJ, Abramson LY. Positive life events, attributional style and hopefulness: testing a model of recovery from depression. J Abnorm Psychol 1990;99(2):156–165.

52. O'Connell RA, Mayo JA, Eng LK, Jones JS, Gabel RH. Social support and long-term lithium outcome. Br J Psychiatry 1985;147:272–275.

53. O'Connell RA, Mayo JA, Flatow L, Cuthbertson B, O'Brien BE. Outcome of bipolar disorder on long-term treatment with lithium. Br J Psychiatry 1991;159:123–129.

54. Parry BL. Reproductive factors affecting the course of affective illness in women. Psychiatr Clin North Am 1989;12(1):207–220.

55. Pasternak RE, Reynolds CF, Schlernitzauer M, et al. Acute open-trial nortriptyline therapy of bereavement-related depression in late life. J Clin Psychiatry 1991;52(7):307–310.

56. Paykel ES, Cooper Z. Life events and social stress. In: Paykel ES, ed. Handbook of affective disorders. New York: Churchill-Livingstone; 1992:149–170.

57. Paykel ES, Myers JK, Dienelt MN, et al. Life events and depression: a controlled study. Arch Gen Psychiatry 1969;21:753–760.

58. Peselow ED, Robins CJ, Sanfilipo MP, Block P, Fieve RR. Sociotropy and autonomy: relationship to antidepressant drug treatment response and endogenous-nonendogenous dichotomy. J Abnorm Psychol 1992;101(3):479–486.

59. Preskorn SH, Mac DS. Plasma levels of amitriptyline: effect of age and sex. J Clin Psychiatry 1985;46(7):276–277.

60. Raskin A. Age-sex differences in response to antidepressant drugs. J Nerv Ment Dis 1974;159(2):120–130.

61. Raskin A, Crook TH. Antidepressants in black and white inpatients. Arch Gen Psychiatry 1975;32:643–649.

62. Regier DA, Farmer ME, Rae DS, et al. Comorbidity of mental disorders with alcohol and other drug abuse. JAMA 1990;264(19): 2511–2518.

63. Robins CJ. Congruence of personality and life events in depression. J Abnorm Psychol 1990;99(4):393–397.

64. Robinson RG, Starkstein SE. Current research in affective disorders following stroke. J Neuropsychiatry Clin Neurosci 1990;2:1–14.

65. Romans SW, McPherson HM. The social networks of bipolar affective disorder patients. J Affect Dis 1992;25(4):221–228.

66. Rounsaville BJ, Weissman MM, Prusoff BA, Herceg-Baron RL. Marital disputes and treatment outcome in depressed women. Compr Psychiatry 1979;20(5):483–490.

67. Smith AL, Weissman MM. Epidemiology. In: Paykel ES, ed. Handbook of affective disorders. New York: Churchill-Livingstone; 1992:111–129.

68. Sotsky SM, Glass DR, Shea T, et al. Patient predictors of response to psychotherapy and pharmacotherapy: findings in the NIMH treatment of depression collaborative research program. Am J Psychiatry 1991;148:997–1008.

69. Vallejo J, Gaston C, Catalan R, Bulbena A, Menchon JM. Predictors of antidepressant treatment outcome in melancholia: psychosocial, clinical and biological indicators. J Affect Dis 1991;21:151–162.

70. Vollrath M, Angst J. Outcome of panic and depression in a seven-year follow-up: results of the Zurich study. Acta Psychiatr Scand 1989;80:591–596.

71. Warheit GJ. Life events, coping, stress, and depressive symptomatology. Am J Psychiatry 1979;136:502–507.

72. Wehr TA, Sack DA, Rosenthal NE, Cowdry RW. Rapid cycling affective disorder: contributing factors and treatment responses in 51 patients. Am J Psychiatry 1988;145(2):179–184.

73. Weissman MM. Panic disorder: impact on quality of life. J Clin Psychiatry Suppl 1991;52(2):6–8.

74. Weissman MM, Klerman GL, Prusoff BA, Sholomskas D, Padian N. Depressed outpatients. Arch Gen Psychiatry 1981;38:51–55.

75. Wells KB, Stewart A, Hays RD, et al. The functioning and well-being of depressed patients. JAMA 1989;262(7):914–918.

76. Wittchen H, Essau CA, von Zerssen D, Krieg J, Zaudig M. Lifetime and six-month prevalence of mental disorders in the Munich follow-up study. Eur Arch Psychiatry Clin Neurosci 1992;241:247–258.

77. Yonkers KA, Kando JC, Cole JO, Blumenthal S. Gender differences in pharmacokinetics and pharmacodynamics of psychotropic medication. Am J Psychiatry 1992;149(5):587–595.

78. Ziegler VE, Biggs JT. Tricyclic plasma levels. Effect of age, race, sex and smoking. JAMA 1977;238:2167–2169.

79. Zisook S, Shuchter SR. Depression through the first year after the death of a spouse. Am J Psychiatry 1991;148(10):1346–1352.