Figure 1

Increased activity in the left prefrontal cortex was found in depressed but not the remitted subjects. Each t-image indicates areas where subjects in the depressed (top) and remitted (bottom) phases of familial pure depressive disease have increased tissue radioactivity relative to the control subjects. Mean voxel t-values for the sagittal planes from 47–51 mm left of the bicommissural line are demonstrated. With permission from Drevets et al. 1992 (25).

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published 2000