TABLE 1. Time course of sleep-wake interventions in affective illness
|
Latency to therapeutic effect |
Duration of therapeutic effect |
Total sleep deprivation |
hours |
usually only 1 day |
Partial sleep deprivation
in the 2nd half of the night |
hours |
usually only 1 day, longer
if repeated |
Phase advance of the
sleep-wake cycle |
3-7 days |
1-2 weeks |
REM sleep deprivation |
2-3 weeks |
months |
Temporal isolation |
3-14 days |
changes with reentrainment |
Total sleep deprivation
followed by phase advance |
1 day |
several days? |
|
Comparison Treatments |
|
Light therapy |
3-4 days |
1 or more weeks |
Antidepressant drugs |
10-30 days |
months |
published 2000