Figure 1. How knowledge of drug-metabolizing enzymes will simplify understanding of pharmacokinetic interactions Reference: (78)

Drug A --- Affects* ® Enzyme X
Enzyme X --- Metabolizes ® Drugs B,C,D,E,F
Therefore Drug A-- Affects* ® Drug B,C,D,E,F,

*Could be inhibition or induction.

 

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published 2000