Table 2.  Human Inonotropic P2X Receptor Subtypes

 

Name

GenBank

Accession #

Agonists

Antagonists

 

P2X1

 

P51575

BzATP,

a,b-meATP

Suramin,

PPADS

 

 

P2X2

 

NA

ATPgS,

2-meS-ATP

PPADS,

Suramin

 

 

P2X3

 

P56373

BzATP,

2-meS-ATP,

ATP

 

TNP-ATP,

PPADS

 

P2X4

 

Q99571

BzATP,

AP3A,

AP4A,

2-meS-ATP

None

 

 

P2X5

 

 

NA

 

None

 

None

 

P2X6

 

 

NA

 

None

 

None

 

P2X7

 

 

Q99572

 

BzATP,

ATP4-

KN-62,

PPADS,

Cibacron Blue

 

NA = Not available

 

 

Back to Chapter

 

published 2000