Purinergic Mechanisms in Nervous System Function and Disease States
Introduction
Purinergic Receptor Dynamics, Interactions, and the Purinergic Cascade
Purine Availability and Modulation
P1 and P2 Receptors
Evolution of Receptor Nomenclature
P1 (ADO) Receptors
P2 (ATP) Receptors
Therapeutic Potential Of Purinoceptor Ligands In Nervous Tissue
Stroke/Ischemia
Epilepsy
Neurodegeneration
ADO Dopamine Interactions: Parkinson's Disease and Psychosis
Sleep
Pain
Challenges in the Development of CNS Selective Therapeutic Agents
Acknowledgments
References
Table of Contents
published 2000