1. Archer R. Principles of evolution: the neural hierarchy model. In: Krieger DT, Brownstein MJ, Martin JB, eds. Brain peptides. New York: John Wiley & Sons, 1983;135–163.

2. Adan RA, Cox JJ, Beischlag TV, Burbach JP. A composite hormone response element mediates the transactivation of the rat oxytocin gene by different classes of nuclear hormone receptors. Mol Endocrinol 1993;7:47–57.

3. Ang HL, Carter DA, Murphy D. Neuron-specific expression and physiological regulation of bovine vasopressin transgenes in mice. EMBO J 1993;12:2397–2409.

4. Antoni FA. Vasopressinergic control of pituitary adrenocorticotropin secretion comes of age. Front Neuroendocrinol 1993;14:76–122.

5. Argiolas A, Gessa GL. Central functions of oxytocin. Neurosci Biobehav Rev 1991;15:217–231.

6. Barberis C, Audigier S, Durroux T, Elands J, Schmidt A, Jard S. Pharmacology of oxytocin and vasopressin receptors in the central and peripheral nervous system. Ann NY Acad Sci 1992;652:39–45.

7. Bohus B, Borrell J, Koolhaas JM, Nyakas C, Buwalda B, Compaan JC, Roozendaal B. The neurohypophysial peptides, learning, and memory processing. Ann NY Acad Sci 1993;689:285–299.

8. Brooks PJ, McCarthy MM, Pfaff DW. Novel approaches to the study of oxytocin neurotransmission in the rat brain. Reg Peptides 1993;45:159–163.

9. Buijs RM, van Heerikhuize JJ. Vasopressin and oxytocin release in the brain—a synaptic event. Brain Res 1982;252:71–76.

10. Buwalda B, Koolhaas JM, Bohus B. Behavioral and cardiac responses to mild stress in young and aged rats: effects of amphetamine and vasopressin. Physiol Behav 1992;51:211–216.

11. Caffé AR, Holstege JC, van Leeuwen FW. Vasopressin immunoreactive fibers and neurons in the dorsal pontine tegmentum of the rat, monkey and human. Prog Brain Res 1991;88:227–240.

12. Coombes JE, Robinson ICAF, Antoni FA, Russell JA. Release of oxytocin into blood and into cerebrospinal fluid induced by naloxone in anaesthetized morphine-dependent rats: the role of the paraventricular nucleus. J Neuroendocrinol 1991;3:551–561.

13. Dantzer R, and Bluthé R-M. Vasopressin and behavior: from memory to olfaction. Regul Pept 1993;45:121–125.

14. Demitrack MA, Lesem MD, Brandt HA, Pigott TA, Jimerson DC, Altemus M, Gold PW. Neurohypophyseal dysfunction: implications for the pathophysiology of eating disorders. Psychopharmacol Bull 1989;25:439–443.

15. De Vries GJ, Duetz W, Buijs RM, Van Heerikhuize J, Breeburg JTM. Effects of androgens and estrogens on the vasopressin and oxytocin innervation of the adult rat brain. Brain Res 1986;399: 296–302.

16. de Wied D, Elands J, Kovács G. Interactive effects of neurohypophyseal neuropeptides with receptor antagonists on passive avoidance behavior: mediation by a cerebral neurohypophyseal hormone receptor? Proc Natl Acad Sci USA 1991;88:1494–1498.

17. Diamant M, de Wied D. Differential effects of centrally injected AVP on heart rate, core temperature, and behavior in rats. Am J Physiol 1993;264:R51–R61.

18. Dreifuss JJ, Raggenbass M. Oxytocin-responsive cells in the mammalian nervous system. Regul Pept 1993;45:109–114.

19. Dubois-Dauphin M, Raggenbass M, Widmer H, Tribollet E, Dreifuss JJ. Morphological and electrophysiological evidence for postsynaptic localization of functional oxytocin receptors in the rat dorsal motor nucleus of the vagus nerve. Brain Res 1992;575:124–131.

20. Fahrbach SE, Morrell JI, Pfaff DW. Possible role for endogenous oxytocin in estrogen-facilitated maternal behavior in rats. Neuroendocrinology 1985;40:526–532.

21. Faiman CP, de-Erausquin GA, Baratti CM. Modulation of memory retrieval by pre-testing vasopressin: involvement of a central cholinergic nicotinic mechanism. Methods Find Exp Clin Pharmacol 1992;14:607–613.

22. Fehm-Wolfsdorf G, Born J. Behavioral effects of neurohypophyseal peptides in healthy volunteers: 10 years of research. Peptides 1991;12:1399–1406.

23. Ferris CF, Axelson JF, Shinto LH, Albers HE. Scent marking and the maintenance of dominant/subordinate status in male golden hamsters. Physiol Behav 1987;40:661–664.

24. Flanagan LM, Dohanics J, Verbalis JG, Stricker EM. Gastric motility and food intake in rats after lesions of hypothalamic paraventricular nucleus. Am J Physiol 1992;263:R39–R44.

25. Flanagan LM, Verbalis JG, Stricker EM. Effects of anorexigenic treatments on gastric motility in rats. Am J Physiol 1989;256:R955–R961.

26. Gibbs DM. Immunoneutralization of oxytocin attenuates stressinduced corticotropin secretion in the rat. Regul Pept 1986;12: 273–277.

27. Gomez RE, Cannata MA, Milner TA, Anwar M, Reis DJ, Ruggiero DA. Vasopressinergic mechanisms in the nucleus reticularis lateralis in blood pressure control. Brain Res 1993;604:90–105.

28. Grant FD, Reventos J, Gordon JW, Kawabata S, Miller M, Majzoub JA. Expression of the rat arginine vasopressin gene in transgenic mice. Mol Endocrinol 1993;7:659–667.

29. Hawthorn J, Ang VTY, Jenkins JS. Effects of lesions in the hypothalamic paraventricular, supraoptic and suprachiasmatic nuclei on vasopressin and oxytocin in rat brain and spinal cord. Brain Res 1985;346:51–57.

30. Helmreich DL, Thiels E, Sved AF, Verbalis JG, Stricker EM. Effect of suckling on gastric motility in lactating rats. Am J Physiol 1991;261:R38–R43.

31. Insel TR, Winslow JT, Williams JR, Hastings N, Shapiro LE, Carter CS. The role of neurohypophyseal peptides in the central mediation of complex social processes—evidence from comparative studies. Regul Pept 1993;45:127–131.

32. Iványi T, Wiegant VM, de Wied D. Differential effects of emotional and physical stress on the central and peripheral secretion of neurohypophysial hormones in male rats. Life Sci 1991;48:1309–1316.

33. Jard S, Gaillard RC, Guillon G, Marie J, Schoenenberg P, Muller AF, Manning M, Sawyer WH. Vasopressin antagonists allow demonstration of a novel type of vasopressin receptor in the rat adenohypophysis. Mol Pharmacol 1986;30:171–180.

34. Jenkins JS, Nussey SS. The role of oxytocin: present concepts. Clin Endocrinol 1991;34:515–525.

35. Jirikowski GF, Sanna PP, Maciejewski-Lenoir D, Bloom FE. Reversal of diabetes insipidus in Brattleboro rats: intrahypothalamic injection of vasopressin mRNA. Science 1992;255:996–998.

36. Kasting NW. Criteria for establishing a physiological role for brain peptides. A case in point: the role of vasopressin in thermoregulation during fever and antipyresis. Brain Res Rev 1989;14:143–153.

37. Kimura T, Tanizawa O, Mori K, Brownstein MJ, Okayama H. Structure and expression of a human oxytocin receptor. Nature 1992;356:526–529.

38. Landgraf R, Malkinson T, Horn T, Veale WL, Lederis K, Pittman QJ. Release of vasopressin and oxytocin by paraventricular stimulation in rats. Am J Physiol 1990;258:R155–R159.

39. Lawrence D, Pittman QJ. Response of rat paraventricular neurones with central projections to suckling, haemorrhage or osmotic stimuli. Brain Res 1985;341:176–183.

40. Legros J-J, Ansseau M, Timsit-Berthier M. Neurohypophyseal peptides and psychiatric diseases. Regul Pept 1993;45:133–138.

41. Lopes da Silva S, De Bree FM, Evans DA, Van Leeuwen FW, Burbach JP. Structure and expression of the vasopressin gene: analysis of mutations, novel genes, and gene products. Ann NY Acad Sci 1993;689:492–503.

42. Loup F, Tribollet E, Dubois-Dauphin M, Dreifuss JJ. Localization of high-affinity binding sites for oxytocin and vasopressin in the human brain. An autoradiographic study. Brain Res 1991;555:220–232.

43. Maciejewski-Lenoir D, Jirikowski GF, Sanna PP, Bloom FE. Reduction of exogenous vasopressin RNA poly(A) tail length increases its effectiveness in transiently correcting diabetes insipidus in the Brattleboro rat. Proc Natl Acad Sci USA 1993;90:1435–1439.

44. Maktabi MA, Elbokl FF, Faraci FM, Todd MM. Halothane decreases the rate of production of cerebrospinal fluid. Possible role of vasopressin V1 receptors. Anesthesiol 1993;78:72–82.

45. Manning M, Chan WY, Sawyer WH. Design of cyclic and linear peptide antagonists of vasopressin and oxytocin: current status and future directions. Regul Pept 1993;45:279–283.

46. Mazurek MF, Beal MF, Bird ED, Martin JB. Oxytocin in Alzheimer's disease—postmortem brain levels. Neurology 1987;37: 1001–1003.

47. McCann MJ, Rogers RC. Oxytocin excites gastric-related neurones in rat dorsal vagal complex. J Physiol 1990;428:95–108.

48. McCann MJ, Verbalis JG, Stricker EM. LiCl and CCK inhibit gastric emptying and feeding and stimulate OT secretion in rats. Am J Physiol 1989;256:R463–R468.

49. Miaskiewicz SL, Stricker EM, Verbalis JG. Neurohypophyseal secretion in response to cholecystokinin but not meal-induced gastric distention in humans. J Clin Endocrinol Metabol 1989;68:837–843.

50. Morel A, O'Carroll A-M, Brownstein MJ, Lolait SJ. Molecular cloning and expression of a rat V1a arginine vasopressin receptor. Nature 1992;365:523–526.

51. Morris JF, Pow DV. Widespread release of peptides in the central nervous system: quantification of tannic acid-captured exocytoses. Anat Rec 1991;231:437–445.

52. Olson BR, Drutarosky MD, Chow M-S, Stricker EM, Hruby VJ, Verbalis JG. Oxytocin and an oxytocin agonist administered centrally decrease food intake in rats. Peptides 1991;12:113–118.

53. Olson BR, Hoffman GE, Sved A, Stricker EM, Verbalis JG. Cholecystokinin induces c-fos expression in hypothalamic oxytocinergic neurons projecting to the dorsal vagal complex. Brain Res 1992;569:238–248.

54. Pedersen CA, Ascher JA, Monroe YL, Prange AJ. Oxytocin induces maternal behavior in virgin female rats. Science 1982;216:648–649.

55. Pettibone DJ, Clineschmidt BV, Bock MG, Evans BE, Freidinger RM, Veber DF, Williams PD. Development and pharmacological assessment of novel peptide and nonpeptide oxytocin antagonists. Regul Pept 1993;45:289–293.

56. Pietrowsky R, Braun D, Fehm HL, Pauschinger P, Born J. Vasopressin and oxytocin do not influence early sensory processing but affect mood and activation in man. Peptides 1991;12:1385–1391.

57. Pittman QJ, Malkinson TJ, Kasting NW, Veale WL. Enhanced fever following castration: possible involvement of brain arginine vasopressin. Am J Physiol 1988;254:R513–R517.

58. Plotsky PM. Regulation of hypophysiotropic factors mediating ACTH secretion. Ann NY Acad Sci 1987;512:205–217.

59. Raggenbass M, Goumaz M, Sermasi E, Tribollet E, Dreifuss JJ. Vasopressin generates a persistant voltage-dependant sodium current in a mammalian motoneurone. J Neurosci 1991;11:1609–1616.

60. Renaud LP, Tang M, McCann MJ, Stricker EM, Verbalis JG. Cholecystokinin and gastric distension activate oxytocinergic cells in rat hypothalamus. Am J Physiol 1987;253:R661–R665.

61. Richard P, Moos F, Freund-Mercier M-J. Central effects of oxytocin. Physiol Rev 1991;71:331–370.

62. Rogers RC, Hermann GE. Central regulation of brainstem gastric vago-vagal control circuits. In: Ritter S, Ritter RC, Barnes CD, eds. Neuroanatomy and physiology of abdominal vagal afferents. Boca Raton, FL: CRC Press, 1992;99–114.

63. Roth J, Schulze K, Simon E, Zeisberger E. Alteration of endotoxin fever and release of arginine vasopressin by dehydration in the guinea pig. Neuroendocrinology 1992;56:680–686.

64. Sanna PP, Jirikowski GF, Maciejewski-Lenoir D, Bloom FE. Expression of exogenous vasopressin mRNA by magno-cellular neurons of the supraoptic and paraventricular nuclei in Brattleboro rats. Ann NY Acad Sci 1992;652:462–465.

65. Sausville E, Carney D, Battey J. The human vasopressin gene is linked to the oxytocin gene and is selectively expressed in a cultured lung cancer cell line. J Biol Chem 1985;260:10236–10241.

66. Sawchenko PE, Arias C, Bittencourt JC. Inhibin b, somatostatin, and enkephalin immunoreactivities coexist in caudal medullary neurons that project to the paraventricular nucleus of the hypothalamus. J Comp Neurol 1990;291:269–280.

67. Sawchenko PE, Swanson LW. The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat. Brain Res Rev 1982;4:275–325.

68. Sawchenko PE, Swanson LW. Immunohistochemical identification of neurons in the paraventricular nucleus of the hypothalamus that project to the medulla or to the spinal cord in the rat. J Comp Neurol 1982;205:260–272.

69. Sawchenko PE, Swanson LW, Vale W. Corticotropin releasing factor: co-expression within distinct subsets of oxytocin-, vasopressin-, and neurotensin-immunoreactive neurons in the hypothalamus of the adult male rat. J Neurosci 1984;4:1118–1129.

70. Stephens LR, Logan SD. Arginine vasopressin stimulates inositol phospholipid metabolism in rat hippocampus. J Neurochem 1986;46:649–651.

71. Stricker EM, Zigmond MJ. Brain monoamines, homeostasis, and adaptive behavior. In: Mountcastle VB, Bloom FE, Geiger SR, eds. Handbook of physiology, section 1: the nervous system. Bethesda, MD: American Physiological Society, 1986;677–700.

72. Swanson LW. The hypothalamus. In: Björklund A, Hökfelt T, Swanson LW, eds. Handbook of chemical neuroanatomy. New York: Elsevier, 1987;5:1–124.

73. Thibonnier M. Vasopressin agonists and antagonists. Horm Res 1990;34:124–128.

74. Tolchard S, Ingram CD. Electrophysiological actions of oxytocin in the dorsal vagal complex of the female rat in vitro: changing responsiveness during the oestrous cycle and after steroid treatment. Brain Res 1993;609:21–28.

75. Tribollet E. Vasopressin and oxytocin receptors in the rat brain. In: Björklund A, Hökfelt T, Kuhar MJ, eds. Handbook of chemical neuroanatomy. New York: Elsevier, 1992;11:289–320.

76. Tribollet E, Audigier S, Dubois-Dauphin M, Dreifuss JJ. Gonadal steroids regulate oxytocin receptors but not vasopressin receptors in the brain of male and female rats. An autoradiographical study. Brain Res 1990;511:129–140.

77. Tribollet E, Dubois-Dauphin M, Dreifuss JJ. Oxytocin receptors in the central nervous system. Distribution, development, and species differences. Ann NY Acad Sci 1992;652:29–38.

78. Van Tol HH, Burbach JP. Quantitation of vasopressin and oxytocin messenger RNA levels in the brain. Methods Enzymol 1989; 168:398–413.

79. Verbalis JG, McCann MJ, McHale CM, Stricker EM. Oxytocin secretion in response to cholecystokinin and food: differentiation of nausea from satiety. Science 1986;232:1417–1419.

80. Verbalis JG, Blackburn RE, Olson BR, Stricker EM. Central oxytocin inhibition of food and salt ingestion: a mechanism for intake regulation of solute homeostasis. Regul Pept 1993;45:149–154.

81. Voorn P, Buijs RM. An immuno-electronmicroscopical study comparing vasopressin, oxytocin, substance-P and enkephalin containing nerve terminals in the nucleus of the solitary tract of the rat. Brain Res 1983;270:169–173.

82. Watts AG, Swanson LW. Efferent projections of the suprachiasmatic nucleus. 1. Studies using anterograde transport of phaseolus vulgaris leucoagglutinin in the rat. J Comp Neurol 1987;258:230–252.

83. Wolters EC, Riekkinen P, Lowenthal A, Van der Plaats JJ, Zwart JMT, Sennef C. DGAVP (Org 5667) in early Alzheimer's disease patients: an international double-blind, placebo-controlled, multicenter trial. Neurology 1990;40:1099–1101.

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