Figure 3. Amino acid sequences of the human CRF2a and CRF2b receptor subtypes. The CRF2a and CRF2b receptor isoforms are shown with the seven putative transmembrane domains. The arrows indicate where the CRF2a and CRF2b receptors diverge at the N-terminus. The amino acids that are unique to the CRF2a receptor are shown in yellow; those unique to the CRF2b receptor are in red.