Table 5:  Effect of Axotomy on Messengers and Receptors in Dorsal
                Root Ganglion Neurons*

Neuropeptide

Axotomy

Substance P

¯(­)

CGRP

¯(­)

Somatostatin

¯

VIP/PHI

­

Galanin

­

CCK

­

NPY

­

PACAP

­

Receptors

d-opioid-R

¯

µ-opioid-R

¯

a_2A-adreno-R

­

a_2C-adreno-R

¯

NPY Y1-R

¯(­)

NPY Y2-R

­

CCK_B-R

­

Galanin R1-R

¯

Galanin R2-R

(¯)

Neurotensin-R

¯

*Arrows indicate up- or downregulation. Brackets indicate weak regulation or opposite regulation in subpopulations of neurons.

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