Fear Induced
Behaviors
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Reduced fearful
Behavior
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With Threat
Fear Conditioning
Chronic Stress
With reduced blood pressure
With elevated CO2
}With blood loss
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The LC-norepinephrine system may help determine
whether, under threat, an individual directs
attention toward external, sensory stimuli or to
internal vegatative events. The system may be
important in facilitating the planning and
execution of behaviors important for survival.
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With Distention of bladder,
colon, rectum
With hypoglycemia
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The LC is a key component in the efferent arm of
the neural circuitry of anxiety. Abnormalities in
noradrenergic function hypothesized to be
involved with pathophysiology of Panic Disorder and PTSD
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