| Figure 6. |
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| Scheme illustrating hypothetical role of DARPP-32, in mediating effects of first messengers with opposing physiological actions, in regulation of Na+/K+-ATPase activity. This scheme, involving bidirectional control of Na+/K+-ATPase activity, may be applicable to various tissues, including brain and kidney. cAMP-PK, cAMP-dependent protein kinase; PKC, protein kinase C. (From Pessin et al., 1993). |
published 2000