Figure 12. |
The binding of [11C]raclopride to D2 receptors in post-mortem schizophrenia striata is not sensitive to the addition of guanine nucleotide. This indicates that schizophrenia tissues have either a low level of dopamine in the synapse or an abnormality in the coupling between the D2 receptor and its G protein. (Adapted from refs. 158,161) |
published 2000