Figure 2 |
Immunoperoxidase
labeling for tyrosine hydroxylase (TH) and immunogold localization of the
dopamine transporter (DAT) in axon terminals in the nucleus accumbens core
of rat brain. A, B: Diffuse peroxidase immunoreactivity
for TH is seen surrounding many small synaptic vesicles in axon terminals
that also show plasmalemmal immunogold particles (small arrows) indicating
the presence of DAT. In A, the dually
labeled terminal is apposed to an unlabeled dendritic spine and presynaptic
terminal (UT) that forms an asymmetric synapse (open arrowhead).
In B, the immunoreactive terminal forms symmetric synapses (curved
arrows) with two unlabeled dendrites (UD).
DAT gold particles are mainly distributed along non-synaptic portions
of the plasma membrane. Bar= 0.2 μm. |
published 2000