Figure 4. |
Injection of low-amplitude, brief hyperpolarizing pulses (top trace) into a nonfiring DA neuron will often evoke rebound action potential discharge (bottom trace; first three events). On the other hand, increases in the amplitude of the hyperpolarizing pulse will eventually trigger the IA-like delayed repolarization of the membrane, effectively blocking the rebound depolarization and spike discharge (third through sixth events). As a consequence, large-amplitude rebound bursts of spikes are not observed in this class of neurons. (From ref. 18, with permission.) |
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published 2000