Functional Heterogeneity of Central Cholinergic Systems
P. B. Reiner and H. C. Fibiger
Division of Neurological Sciences
Department of Psychiatry
University of British Columbia
Vancouver, B.C. V6T 1Z3, Canada.
REFERENCES
1. Araujo DM, Lapchak PA, Robitaille Y, Gauthier S, Quirion R. Differential alteration of various cholinergic markers in cortical and subcortical regions of human brain in Alzheimer's disease. J Neurochem 1988;50:1914–1923.
2. Ball MJ, Hachinski V, Fox A, et al. A new definition of Alzheimer's disease: a hippocampal dementia. Lancet 1985;8419:14–16.
3. Bartus RT, Dean RL, Beer B, Lippa AS. The cholinergic hypothesis of geriatric memory dysfunction. Science 1982;217:408–417.
4. Batchelor PE, Armstrong DM, Blaker SN, Gage FH. Nerve growth factor receptor and choline acetyltransferase colocalization in neurons within the rat forebrain: response to fimbria–fornix transection. J Comp Neurol 1989;284:187–204.
5. Blokland A, Honig W, Raaijmakers WGM. Effects of intrahippocampal scopolamine injections in a repeated spatial acquisition task in the rat. Psychopharmacology 1992;109:373–376.
6. Brito GNO, Davis BJ, Stopp LC, Stanton ME. Memory and the septohippocampal cholinergic system in the rat. Psychopharmacology 1983;82:315–320.
7. Buzsaki G, Bickford RG, Ponomareff G, Thal LJ, Mandel R, Gage FH. Nucleus basalis and thalamic control of neocortical activity in the freely moving rat. J Neurosci 1988;8:4007–4026.
8. Celesia GG, Jasper HH. Acetylcholine released from cerebral cortex in relation to state of activation. Neurology 1966;16:1053–1063.
9. Coyle JT, Price DL, DeLong MR. Alzheimer's disease: a disorder of cortical cholinergic innervation. Science 1983;219:1184–1190.
10. Day J, Damsma G, Fibiger HC. Cholinergic activity in the rat hippocampus, cortex and striatum correlates with locomotor activity: an in vivo microdialysis study. Pharmacol Biochem Behav 1991;38:723–729.
11. Day J, Fibiger HC. Dopaminergic regulation of cortical acetylcholine release. Synapse 1992;12:281–286.
12. Day J, Fibiger HC. Dopaminergic regulation of cortical acetylcholine release: effects of dopamine receptor agonist. Neuroscience 1993;54:643–648.
13. Detari L, Vanderwolf CH. Activity of identified cortically projecting and other basal forebrain neurones during large slow waves and cortical activation in anaesthetized rats. Brain Res 1987;437:1–8.
14. Deutch JA. The cholinergic synapse and the site of memory. Science 1971;174:788–794.
15. Drachman DA, Sahakian BJ. Memory, aging and pharmacosystems. In: Stein D, ed. The psychobiology of aging: problems and perspectives. Amsterdam: Elsevier/North-Holland, 1980;347–368.
16. Dunne MP, Hartley LR. Scopolamine and the control of attention in humans. Psychopharmacology 1986;89:94–97.
17. Dunnett SB, Wareham AT, Torres EM. Cholinergic blockade in prefrontal cortex and hippocampus disrupts short-term memory in rats. NeuroReport 1990;1:61–64.
18. Dunnett SB, Everitt BJ, Robbins TW. The basal forebrain–cortical cholinergic system: interpreting the functional consequences of excitotoxic lesions. Trends Neurosci 1991;14:494–501.
19. Dunnett SB, Fibiger HC. Role of forebrain cholinergic systems in learning and memory: relevance to the cognitive deficits of aging and Alzheimer's dementia. Prog Brain Res 1993;98:413–420.
20. El-Mansari M, Sakai K, Jouvet M. Unitary characteristics of presumptive cholinergic tegmental neurons during the sleep–waking cycle in freely moving cats. Exp Brain Res 1989;76:509–529.
21. Fibiger HC. Central cholinergic systems and memory. In: Squire LR, Lindenlaub E, eds. The biology of memory, Symposia Medica Hoechst 23. New York: Springer-Verlag, 1990;381–398.
22. Fibiger HC. Cholinergic mechanisms in learning, memory and dementia: a review of recent evidence. Trends Neurosci 1991;14:220–223.
23. Gerfen CR. Substance P (neurokinin-1) receptor mRNA is selectively expressed in cholinergic neurons in the striatum and basal forebrain. Brain Res 1991;556:165–170.
24. German DC, White III CL, Sparkman DR. Alzheimer's disease: neurofibrillary tangles in nuclei that project to the cerebral cortex. Neuroscience 1987;21:305–312.
25. Geula C, Schatz CR, Mesulam M-M. Differential localization of NADPH-diaphorase and calbindin-D28k within the cholinergic neurons of the basal forebrain, striatum and brainstem in the rat, monkey, baboon and human. Neuroscience 1993;54:461–476.
26. Gottfries CG. Neurochemical aspects of dementia disorders [Review]. Dementia 1990;1:56–64.
27. Hagan JJ, Morris RGM. The cholinergic hypothesis of memory: a review of animal experiments. In: Iversen LL, Iversen SD, Snyder SH, eds. Handbook of psychopharmacology, vol 20. New York: Plenum Press, 1988;217–323.
28. Hallanger AE, Levey AI, Lee HJ, Rye DB, Wainer BH. The origins of the cholinergic and other subcortical afferents to the thalamus in the rat. J Comp Neurol 1987;262:105–124.
29. Jones BE, Beaudet A. Distribution of acetylcholine and catecholamine neurons in the cat brain stem: a choline acetyltransferase and tyrosine hydroxylase immunohistochemical study. J Comp Neurol 1987;261:15–32.
30. Kainai T, Szerb JC. Mesencephalic reticular activating system and cortical acetylcholine output. Nature 1965;205:80–82.
31. Kamondi A, Williams JA, Hutcheon B, Reiner PB. Membrane properties of mesopontine cholinergic neurons studied with the whole-cell patch-clamp technique: implications for behavioral state control. J Neurophysiol 1992;68:1359–1372.
32. Khateb A, Muhlethaler M, Alonso A, Serafin M, Mainville L, Jones BE. Cholinergic nucleus basalis neurons display the capacity for rhythmic bursting activity mediated by low-threshold calcium spikes. Neuroscience 1992;51:489–494.
33. Longo VG. Behavioral and electroencephalographic effects of atropine and related compounds. Pharmacol Rev 1966;18:965–996.
34. Luebke JI, Greene RW, Semba K, Kamondi A, McCarley RW, Reiner PB. Serotonin hyperpolarizes cholinergic low threshold burst neurons in the rat laterodorsal tegmental nucleus in vitro. Proc Natl Acad Sci USA 1992;89:743–747.
35. Martin LJ, Blackstone CD, Levey AI, Huganir RL, Price DL. Cellular localizations of AMPH glutamate receptors within the basal forebrain magnocellular complex of rat and monkey. J Neurosci 1993;13:2249–2263.
36. McCormick DA. Cholinergic and noradrenergic modulation of thalamocortical processing. Trends Neurosci 1989;12:215–221.
37. Melander T, Staines WA, Hökfelt T, et al. Galanin-like immunoreactivity in cholinergic neurons of the septum–basal forebrain complex projecting to the hippocampus of the rat. Brain Res 1985;360:130–138.
38. Mishkin M. A memory system in the monkey. Philos Trans R Soc Lond [Biol] 1982;298:83–95.
39. Moruzzi G, Magoun HW. Brainstem reticular formation and activation of the EEG. Electroencephalogr Clin Neurophysiol 1949; 1:455–473.
40. Muir JL, Everitt BJ, Robbins TW. AMPA-induced excitotoxic lesions of the basal forebrain: a significant role for the cortical cholinergic system in attentional function. J Neurosci 1994;14:2313–2326.
41. Newhouse PA, Belenky G, Thomas M, Thorne D, Sing HC, Fertig J. The effects of d-amphetamine on arousal, cognition, and mood after prolonged total sleep deprivation. Neuropsychopharmacology 1989;2:153–164.
42. Olton DS, Becker JT, Handelmann GE. Hippocampus, space, and memory. Behav Brain Sci 1979;2:313–365.
43. Pare D, Steriade M, Deschenes M, Bouhassira D. Prolonged enhancement of anterior thalamic synaptic responsiveness by stimulation of a brain-stem cholinergic group. J Neurosci 1990;10:20–33.
44. Pasqualotto BA, Vincent SR. Galanin and NADPH-diaphorase coexistence in cholinergic neurons of the rat basal forebrain. Brain Res 1991;551:78–86.
45. Pearson RCA, Esiri MM, Hiorns RW, Wilcock GK, Powell TPS. Anatomical correlates of the distribution of the pathological changes in the neocortex. Proc Natl Acad Sci USA 1985;82:4531–4534.
46. Preda L, Alberoni M, Bressi S, et al. Effects of acute doses of oxiracetam in the scopolamine model of human amnesia. Psychopharmacology 1993;110:421–426.
47. Reiner PB, Vincent SR. Topographic relations of cholinergic and noradrenergic neurons in the feline pontomesencephalic tegmentum: an immunohistochemical study. Brain Res Bull 1987;19:705–714.
48. Richardson RT, DeLong MR. Nucleus basalis of Meynert neuronal activity during a delayed response task in monkey. Brain Res 1986;399:364–368.
49. Richardson RT, DeLong MR. A reappraisal of the functions of the nucleus basalis of Meynert. Trends Neurosci 1988;11:264–267.
50. Richardson RT, DeLong MR. Context-dependent responses of primate nucleus basalis neurons in a go/no-go task. J Neurosci 1990;10:2528–2540.
51. Riekkinnen Jr. P, Sirvio J, Hannila T, Miettinen R, Riekkinen P. Effects of quisqualic acid nucleus basalis lesioning on cortical EEG, passive avoidance and water maze performance. Brain Res Bull 1990;24:839–842.
52. Robbins TW, Everitt BJ, Marston HM, Wilkinson J, Jones GH, Page KJ. Comparative effects of ibotenic acid- and quisqualic acid-induced lesions of the substantia innominata on attentional function in the rat: further implications for the role of the cholinergic neurons of the nucleus basalis in cognitive processes. Behav Brain Res 1989;35:221–240.
53. Rolls ET, Sanghera MK, Roper-Hall A. The latency of activation of neurones in the lateral hypothalamus and substantia innominata during feeding in the monkey. Brain Res 1979;164:121–135.
54. Sahakian BJ, Owen AM, Morant NJ, et al. Further analysis of the cognitive effects of tetrahydroaminoacridine (THA) in Alzheimer's disease: assessment of attentional and mnemonic function using CANTAB. Psychopharmacology 1993;110:395–401.
55. Satoh K, Fibiger HC. Cholinergic neurons of the laterodorsal tegmental nucleus: efferent and afferent connections. J Comp Neurol 1986;253:277–302.
56. Schwaber JS, Rogers WT, Satoh K, Fibiger HC. Distribution and organization of cholinergic neurons in the rat forebrain demonstrated by computer-aided data acquisition and three-dimensional reconstruction. J Comp Neurol 1987;263:309–325.
57. Semba K, Fibiger HC. Time of origin of cholinergic neurons in the rat basal forebrain. J Comp Neurol 1988;269:87–95.
58. Shute CCD, Lewis PR. The ascending cholinergic reticular system: neocortical, olfactory and subcortical projections. Brain 1967; 90:497–520.
59. Steriade M, Datta S, Pare D, Oakson G, Dossi RC. Neuronal activities in brain-stem cholinergic nuclei related to tonic activation processes in thalamocortical systems. J Neurosci 1990;10:1541–1559.
60. Steriade M, Jones EG, Llinas RR. Thalamic oscillations and signalling. New York: John Wiley & Sons, 1990.
61. Steriade M, McCarley RW. Brainstem control of wakefulness and sleep. New York: Plenum Press, 1990.
62. Stewart DJ, MacFabe DF, Vanderwolf CH. Cholinergic activation of the electrocorticogram: role of substantia innominata and effects of atropine and quinuclidinyl benzylate. Brain Res 1984;322:219–232.
63. Stewart M, Fox SE. Do septal neurons pace the hippocampal theta rhythm? Trends Neurosci 1990;13:163–168.
64. Sykes DH, Douglas VI, Morgenstern G. The effect of methylphenidate (Ritalin) on sustained attention in hyperactive children. Psychopharmacologia 1972;25:262–274.
65. Szymusiak R, McGinty D. Sleep–waking discharge of basal forebrain projection neurons in cats. Brain Res Bull 1989;22:423–430.
66. Terry RD, Katzman R. Senile dementia of the Alzheimer's type. Ann Neurol 1983;14:497–506.
67. Toran-Allerand CD, Miranda RC, Bentham WDL, et al. Estrogen receptors colocalize with low-affinity nerve growth factor receptors in cholinergic neurons of the basal forebrain. Proc Natl Acad Sci USA 1992;89:4668–4672.
68. Vanderwolf CH. Cerebral activity and behavior: control by central cholinergic and serotonergic systems. Int Rev Neurobiol 1988; 30:225–340.
69. Vanderwolf CH, Raithby A, Snider M, Cristi C, Tanner C. Effects of some cholinergic agonists on neocortical slow wave activity in rats with basal forebrain lesions. Brain Res Bull 1993;31:515–521.
70. Vanderwolf CH, Robinson TH. Reticulocortical activity and behavior: a critique of the arousal theory and a new synthesis. Behav Brain Sci 1981;4:459–514.
71. Walker LC, Rance NE, Price DL, Young WS. Galanin mRNA in the nucleus basalis of Meynert complex of baboons and humans. J Comp Neurol 1991;303:113–120.
72. Webster HH, Jones BE. Neurotoxic lesions of the dorsolateral pontomesencephalic tegmentum–cholinergic cell area in the cat. II. Effects upon sleep–waking states. Brain Res 1988;458:285–302.
73. Wilson FAW, Rolls ET. Neuronal responses related to reinforcement in the primate basal forebrain. Brain Res 1990;509:213–231.
74. Wilson FAW, Rolls ET. Learning and memory is reflected in the responses of reinforcement-related neurons in the primate basal forebrain. J Neurosci 1990;10:1254–1267.
published 2000