TABLE 2. Dissociation constants of subtype selective muscarinic antagonists in transfected murine fibroblastsa

-Log (KD)

Antagonists

M1

M2

M3

M4

M5

Atropine

9.29

9.00

9.28

9.66

9.43

Pirenzepine

7.89

6.38

6.72

7.07

7.06

AF-DX 116

6.27

7.04

5.95

6.54

5.66

HHSiD

7.85

6.71

7.99

7.69

7.37

4-DAMP

8.92

8.21

9.19

9.15

8.92

a Data were taken from Kashihara et al. (41).

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published 2000